Actively Recruiting

Age: 18Years +
All Genders
NCT06862869

Real World Clinical Outcomes of Resected ALK-Positive Early Stage NSCLC Patients Treated With Alectinib as Adjuvant Therapy

Led by Hoffmann-La Roche · Updated on 2026-05-05

800

Participants Needed

41

Research Sites

208 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study is a multicenter, prospective, cohort study designed to evaluate the clinical outcomes and characteristics of resected stage II-IIIB anaplastic lymphoma kinase (ALK)-positive non-small-cell lung cancer (NSCLC) adult patients treated with Alectinib as adjuvant therapy in China.

CONDITIONS

Official Title

Real World Clinical Outcomes of Resected ALK-Positive Early Stage NSCLC Patients Treated With Alectinib as Adjuvant Therapy

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Histologically-confirmed stage II-IIIA or selected IIIB (T3N2) non-small-cell lung cancer
  • ALK-positive status confirmed
  • Postoperative patients who have undergone complete tumor resection
  • Patients treated with Alectinib monotherapy as adjuvant therapy without prior systemic treatment
  • Time from first Alectinib dose to enrollment is no more than 28 days
Not Eligible

You will not qualify if you...

  • Participation in any interventional study of adjuvant treatment
  • Pregnant, lactating, or breastfeeding women

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 41 locations

1

Affiliated Hospital of Guangdong Medical University

Zhanjiang, Guangdong, China, 524001

Actively Recruiting

2

Affiliated Cancer Hospital and Institute of Guangzhou Medical University

Guangzhou, Guangzhou, China, 510095

Actively Recruiting

3

Huai He Hospital of Henan University

Kaifeng, Henan, China, 475001

Actively Recruiting

4

Henan Provincial Chest Hospital

Zhengzhou, Henan, China, 450003

Actively Recruiting

5

The First Affiliated Hospital of Xinjiang Medical University

Ürümqi, Xinjiang, China, 830054

Actively Recruiting

6

Peking University First Hospital

Beijing, China, 100034

Actively Recruiting

7

Xuanwu Hospital, Capital Medical University

Beijing, China, 100053

Active, Not Recruiting

8

Hunan Cancer Hospital

Changsha, China, 410013

Actively Recruiting

9

Changzhou First People's Hospital

Changzhou, China, 213003

Actively Recruiting

10

Sichuan Academy of Medical Sciences and Sichuan Provincial Peoples Hospital

Chengdu, China, 610072

Actively Recruiting

11

The First Affiliated Hospital, Chongqing Medical University

Chongqing, China, 400016

Actively Recruiting

12

The Second Affiliated Hospital of Dalian Medical University

Dalian, China, 116027

Actively Recruiting

13

Fujian Cancer Hospital

Fuzhou, China, 350014

Actively Recruiting

14

The Third Affiliated Hospital of Sun Yat-Sen University

Guangzhou, China, 510630

Actively Recruiting

15

The Second Affiliated Hospital, Zhejiang University

Hangzhou, China, 310009

Actively Recruiting

16

Zhejiang Cancer Hospital

Hangzhou, China, 310022

Actively Recruiting

17

Harbin Medical University Cancer Hospital

Harbin, China, 150081

Actively Recruiting

18

Anhui Provincial Hospital

Hefei, China, 230001

Actively Recruiting

19

Huzhou Central Hospital

Huzhou, China, 313000

Actively Recruiting

20

Jiangmen Central Hospital

Jiangmen, China, 529030

Actively Recruiting

21

Shandong Provincial Hospital

Jinan, China, 250021

Actively Recruiting

22

Lanzhou University Second Hospital

Lanzhou, China, 730030

Actively Recruiting

23

The First Affiliated Hospital of Nanchang University

Nanchang, China

Actively Recruiting

24

Jiangsu Cancer Hospital

Nanjing, China, 210000

Actively Recruiting

25

Jiangsu Province Hospital

Nanjing, China, 210008

Actively Recruiting

26

Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School

Nanjing, China, 210008

Actively Recruiting

27

Affiliated Hospital of Nantong University

Nantong, China, 226001

Actively Recruiting

28

Ningbo No.2 Hospital

Ningbo, China, 315000

Actively Recruiting

29

Shanghai Chest Hospital

Shanghai, China, 200030

Actively Recruiting

30

Zhongshan Hospital Fudan University

Shanghai, China, 200032

Actively Recruiting

31

Shanghai Pulmonary Hospital

Shanghai, China, 200433

Actively Recruiting

32

Liaoning Provincial Cancer Hospital

Shengyang, China, 110042

Actively Recruiting

33

Hebei Medical University Fourth Hospital

Shijiazhuang, China, 50011

Actively Recruiting

34

Shanxi Provincial Cancer Hospital

Taiyuan, China, 030013

Actively Recruiting

35

Taizhou Hospital of Zhejiang Province

Taizhou, China, 317000

Actively Recruiting

36

Chest disease hospital of Tianjin City

Tianjin, China

Actively Recruiting

37

Tongji Hospital affiliated to Tongji Medical College of Huazhong University of Science & Technology

Wuhan, China, 430030

Actively Recruiting

38

Wuxi People's Hospital

Wuxi, China, 214023

Actively Recruiting

39

Xi'an International Medical Center Hospital

Xi'an, China, 710100

Actively Recruiting

40

General Hospital of Ningxia Medical University

Yinchuan, China, 750004

Actively Recruiting

41

Affiliated Hospital of Zunyi Medical University

Zunyi, China, 563000

Actively Recruiting

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Research Team

R

Reference Study ID Number: ML45766 https://forpatients.roche.com/

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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