Actively Recruiting

Age: 18Years +
All Genders
NCT06783335

Real World Effectiveness of the Cordella Pulmonary Artery Sensor System in Patients With Chronic Heart Heart Failure

Led by Endotronix, Inc. · Updated on 2025-11-19

2150

Participants Needed

1

Research Sites

307 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This retrospective, non-randomized cohort study will evaluate how well the Cordella PA Sensor System works compared to standard medication treatment in people with chronic heart failure. The study will track patients for two years to see if those using the Cordella system have fewer deaths and hospitalizations related to heart failure.

CONDITIONS

Official Title

Real World Effectiveness of the Cordella Pulmonary Artery Sensor System in Patients With Chronic Heart Heart Failure

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Received Cordella PA Sensor System implant between 10/1/2024 and 12/31/2029
  • Documented chronic heart failure with NYHA Class III symptoms
  • On guideline-directed medical therapy based on ejection fraction status
  • For reduced EF (≤40%): at least one fill of ACE/ARB/ARNI, MRA, BB, or SGLT2i, and one fill of a loop diuretic
  • For preserved EF (>40%): at least one fill of a loop diuretic
  • Has continuous health insurance enrollment for 12 months prior to implant
  • Two or more encounters with diagnosis codes for chronic systolic and/or diastolic heart failure (Standard of Care Control Cohort)
  • Documented ejection fraction reading within 6 months (+ or -) of second heart failure encounter (Standard of Care Control Cohort)
  • Has continuous health insurance enrollment for 12 months prior to study entry (Standard of Care Control Cohort)
Not Eligible

You will not qualify if you...

  • No implanted pulmonary artery sensor or monitoring at any time (Standard of Care Control Cohort only)
  • Record of temporary mechanical circulatory support during baseline period
  • Diagnosis of cardiogenic shock during baseline period
  • Receiving palliative care or hospice during baseline period
  • Record of end-stage renal disease during baseline period
  • Unable to take dual antiplatelet therapy or anticoagulants for one month post implant (Cordella Cohort only)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

Endotronix

Naperville, Illinois, United States, 60563

Actively Recruiting

Loading map...

Research Team

A

Andrea Sauerland

CONTACT

M

Max Gill

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here