Actively Recruiting

Phase 4
Age: 18Years +
All Genders
NCT06928753

Real-world Effectiveness, Safety and Immunogenicity of Chikungunya Vaccination in Populations at Risk of Severe or Complicated Forms: Prospective Study in La Réunion

Led by Centre Hospitalier Universitaire de la Réunion · Updated on 2025-07-29

1800

Participants Needed

1

Research Sites

75 weeks

Total Duration

On this page

Sponsors

C

Centre Hospitalier Universitaire de la Réunion

Lead Sponsor

A

ANRS, Emerging Infectious Diseases

Collaborating Sponsor

AI-Summary

What this Trial Is About

Against the backdrop of a growing chikungunya epidemic in La Réunion, this prospective study will assess the real-life efficacy, safety and immunogenicity of IXCHIQ® vaccine in vulnerable individuals (seniors, comorbid patients), defined by the French Health Autority (HAS) as at risk of severe or complicated forms and/or chronic disabling forms (chronic arthritis, chronic fatigue phenotypes). This study will also provide input for the preparation of a cluster randomized trial on a population scale.

CONDITIONS

Official Title

Real-world Effectiveness, Safety and Immunogenicity of Chikungunya Vaccination in Populations at Risk of Severe or Complicated Forms: Prospective Study in La Réunion

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Eligible for anti-chikungunya vaccination according to french Health Authority (HAS)
  • Beneficiary of social security coverage
  • Signature of informed consent form
Not Eligible

You will not qualify if you...

  • Pregnant women
  • Vaccine contraindication for patients undergoing medical treatment
  • Persons under guardianship, curatorship or safeguard of justice
  • Anyone who has received immunoglobulin or a blood or plasma transfusion 3 months prior to vaccine administration

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

CHU La Réunion

Saint-Denis, France

Actively Recruiting

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Research Team

P

Patrick GERARDIN, MD

CONTACT

F

Florence LEFEBVRE D'HELLENCOURT

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

2

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