Actively Recruiting

Age: 40Years +
All Genders
NCT07406048

Real-World Effectiveness of a Triple Combination BDP/FF/GB Extrafine in a Single Pressurised Metered Dose Inhaler in Brazilian COPD Patients

Led by Chiesi Farmaceutica Ltda. · Updated on 2026-04-17

396

Participants Needed

1

Research Sites

65 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This multicenter, retrospective-prospective, cohort study aims to evaluate the effectiveness and safety of Extra-fine Beclometasone Diproprionate/Formoterol Fumarate/Glycopyrronium Bromide (EF-BDP/FF/GB) therapy in adults with severe or very severe COPD in Brazil. Around 400 patients will be enrolled across approximately 15 sites. Eligible patients must have started treatment on the day of enrollment or up to three months before enrollment. Data will be collected both retrospectively and prospectively, with baseline information covering up to 12 months before treatment initiation. All assessments will occur during routine medical visits, with follow-up expected at approximately 3 ± 1 month and 6 months ± 2 months. The medication Trimbow® will not be provided as part of the study and must be prescribed and used according to the institution's standard clinical practice, regardless of participation in the study.

CONDITIONS

Official Title

Real-World Effectiveness of a Triple Combination BDP/FF/GB Extrafine in a Single Pressurised Metered Dose Inhaler in Brazilian COPD Patients

Who Can Participate

Age: 40Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Male and female patients aged 40 years or older at the time of starting BDP/FF/GB treatment
  • Documented diagnosis of severe or very severe COPD before starting BDP/FF/GB
  • COPD Assessment Test (CAT) total score of 10 or higher at baseline or within 12 months before treatment
  • At least one COPD exacerbation in the 12 months before enrollment
  • Started treatment with BDP/FF/GB within 3 months before or on the date of signing informed consent
  • Willing and able to provide written consent to participate in the study
Not Eligible

You will not qualify if you...

  • Participation in any interventional study during this study period or in the 3 months before starting BDP/FF/GB

AI-Screening

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Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Santa Casa de Misericórdia de São Paulo

São Paulo, São Paulo, Brazil, 01221-020

Actively Recruiting

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Research Team

I

ISMAEL PRETTO SAUTER

CONTACT

M

Medical Information Chiesi

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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