Actively Recruiting
Real-world Experience Using Nemolizumab in the Treatment of Moderate-to-Severe Atopic Dermatitis in Adolescents Adults
Led by Galderma R&D · Updated on 2026-03-13
1000
Participants Needed
108
Research Sites
55 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating the real-world use of nemolizumab for treating moderate-to-severe atopic dermatitis AD in adolescents and adults. This observational study aims to assess the treatments effectiveness through physician evaluations and patient-reported outcomes over six months, providing insight into how the medication performs in everyday clinical practice. Participants receiving nemolizumab as part of their routine care will be observed for about 12 months. Treatment decisions are made by the participants physician before joining the study, with no extra visits or tests beyond usual medical care. A sub-study in Germany and the UK involves daily remote reporting of symptoms such as peak and average itch, sleep disturbance, and pain for the first two weeks. During the study, participants will have regular medical visits as determined by their doctors, with data collected from routine assessments and patient questionnaires. Researchers will measure outcomes like the Investigator Global Assessment and Peak Pruritus Numerical Rating Scale at six months, along with other severity and symptom scores up to 12 months. No additional procedures outside standard care are required, allowing for natural monitoring of treatment effects and safety.
CONDITIONS
Brief Title
Real-world Experience Using Nemolizumab in the Treatment of Moderate-to-Severe Atopic Dermatitis in Adolescents & Adults
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participants starting treatment with nemolizumab as decided by their doctor and following local guidelines
- Adolescents and adults aged 12 years or older with moderate-to-severe atopic dermatitis
- Participants who have signed informed consent or have consent from a legal representative
You will not qualify if you...
- Contraindications for nemolizumab according to local guidelines
- Received treatment with an investigational drug within 3 months before baseline
- Previously treated with nemolizumab
- Unable mentally, physically, or linguistically to understand consent or complete study questionnaires
Research Team
G
Galderma Research and Development
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