Actively Recruiting
A Real-World Study Comparing the Efficacy of Different Treatment Regimens for Early Missed Abortion
Led by The Third Xiangya Hospital of Central South University · Updated on 2026-02-20
580
Participants Needed
1
Research Sites
574 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
At present, there is no unified standard for the treatment of missed abortion in clinical practice. This study intends to collect clinical data of this type of disease to compare the efficacy of different treatments, and on this basis, presuppose the synergistic effect of different doses of estrogen in the process of drug induction, conduct statistical analysis of the efficacy, evaluate whether the treatment plan can achieve the therapeutic effect while reducing the occurrence of complications, and provide an effective basis for the subsequent clinical treatment of missed abortion. This study is divided into two parts. The first part is a retrospective analysis to explore the differences between missed abortion surgery and drug treatment, clinical efficacy and reproductive outcomes; the second part is a prospective study to explore the effects of different doses of estrogen combined with surgery or drug abortion on the efficacy of missed abortion in early pregnancy, and explore the best clinical treatment method for missed abortion.
CONDITIONS
Official Title
A Real-World Study Comparing the Efficacy of Different Treatment Regimens for Early Missed Abortion
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18-40 years old
- Early pregnancy missed abortion confirmed by imaging and laboratory tests
- All routine examination results before treatment are within normal range with no serious systemic diseases
- No emergency curettage needed
- Good compliance and able to follow required follow-up (prospective study)
You will not qualify if you...
- Contraindications to medical abortion
- Allergy to estrogen or contraindications to estrogen use
- Unable to follow up as required
- History or suspicion of thromboembolic diseases, breast cancer, or hormone-dependent tumors
- Vaginal bleeding exceeding normal menstrual volume
- Severe heart, liver, or kidney diseases
- Serious internal or surgical diseases, malignant tumors, or mental illnesses preventing cooperation
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
The Third Xiangya Hospital of Central South University
Changsha, Hunan, China, 410013
Actively Recruiting
Research Team
D
Dabao Xu
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
4
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