Actively Recruiting
Real-World Study on Nano-Crystalline Megestrol Acetate for Cachexia in TKI-Treated Advanced Digestive Tumors
Led by Changchun GeneScience Pharmaceutical Co., Ltd. · Updated on 2025-04-23
120
Participants Needed
2
Research Sites
89 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study is a prospective, observational clinical study aimed at evaluating the efficacy of Megestrol Acetate for cachexia in patients with advanced digestive system tumors receiving TKI-based therapy.
CONDITIONS
Official Title
Real-World Study on Nano-Crystalline Megestrol Acetate for Cachexia in TKI-Treated Advanced Digestive Tumors
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Voluntarily sign a written informed consent
- Age 18 years or older at enrollment
- Eastern Cooperative Oncology Group (ECOG) performance status of 0-2
- Life expectancy of 3 months or more
- Histologically or cytologically confirmed locally advanced or metastatic digestive system tumors not suitable for curative treatment
- Not benefiting from local anticancer therapies and planned to receive TKI-based anticancer treatment (possibly combined with chemotherapy or immunotherapy)
- Meet diagnostic criteria for pre-cachexia or cachexia based on Fearon criteria
- Good organ function
You will not qualify if you...
- Gastrointestinal obstruction
- Anorexia caused by difficulty eating due to neurosis, mental illness, or pain
- Severe cerebrovascular, cardiac, renal, or liver diseases
- Major surgery or trauma within the last month
- Allergy to any component of the investigational drug
- Other conditions deemed unsuitable by the investigator
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
General Hospital of Northern Theater Command
Shenyang, Liaoning, China, 110016
Actively Recruiting
2
Liaoning Cancer Hospital
Shenyang, Liaoning, China, 110042
Actively Recruiting
Research Team
C
Cheng Du
CONTACT
Z
Zhenguang Du
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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