Actively Recruiting

Age: 18Years +
All Genders
NCT05879757

Real-world Usage of HyQvia in Multiple Myeloma Adults With Secondary Immunodeficiency

Led by Takeda · Updated on 2026-02-18

75

Participants Needed

27

Research Sites

174 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

In this study, multiple myeloma participants with secondary immunodeficiency (SID) will be treated with HyQvia according to their clinic's standard practice. The study's main aim is to look into infusion parameters of HyQvia administration.

CONDITIONS

Official Title

Real-world Usage of HyQvia in Multiple Myeloma Adults With Secondary Immunodeficiency

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Able and willing to provide informed consent, or consent provided by legally authorized representative
  • Diagnosed with multiple myeloma requiring systemic anti-myeloma therapy as per IMWG criteria
  • Started HyQvia treatment no more than 30 days before enrollment or within 30 days after enrollment, with no more than 2 doses received
  • Age 18 years or older at the time of multiple myeloma diagnosis
  • Medical history available from time of multiple myeloma diagnosis requiring treatment
  • Life expectancy greater than 6 months at enrollment as assessed by physician
  • Eastern Cooperative Oncology Group (ECOG) performance status score of 2 or less
  • Willing and able to comply with study requirements
Not Eligible

You will not qualify if you...

  • Known hypersensitivity to any components of HyQvia
  • Primary immunodeficiency or diagnosed with HIV/AIDS, active hepatitis B or C infection
  • Use of immunoglobulin treatment or prophylaxis within 3 months before enrollment
  • Serious infections requiring intravenous treatment at enrollment, except short-term oral antibiotics
  • Participation in an interventional clinical study involving medicinal products or devices within 30 days before enrollment or planned during this study (except CAR-T cell therapies or bispecific antibodies)
  • Planned stem cell transplant during treatment or prior stem cell transplant: any allogeneic transplant or autologous transplant within 3 months
  • History of malignancy other than multiple myeloma within 3 years before enrollment, except certain skin cancers, carcinoma in situ, localized prostate cancer, or other low-risk lesions
  • Major surgery within 2 weeks before enrollment or not fully recovered from earlier surgery, or planned major surgery during study participation (local anesthesia surgeries allowed; kyphoplasty and vertebroplasty excluded)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 27 locations

1

Instituto Privado de Investigaciones Clinicas de Cordoba

Córdoba, Argentina, X5000AAW

Withdrawn

2

Fakultni nemocnice Plzen

Pilsen, Czechia, 30460

Actively Recruiting

3

Vseobecna fakultni Nemocnice

Prague, Czechia, 128 08

Not Yet Recruiting

4

CHU Amiens - Hopital Sud

Salouël, Somme, France, 80480

Actively Recruiting

5

CHU Dijon - Hopital du Bocage

Dijon, France, 21079

Not Yet Recruiting

6

Hopital Prive du Confluent

Nantes, France, 44 277

Actively Recruiting

7

Hopital de la Source - CHR Orleans

Orléans, France, 45067

Not Yet Recruiting

8

CHU Bordeaux - Hopital Haut-Leveque

Pessac, France, 33604

Not Yet Recruiting

9

MHP-Muenchner Haematologiepraxis

Berlin, Germany, 10117

Not Yet Recruiting

10

Alexandra General Hospital

Athens, Greece, 11528

Actively Recruiting

11

General Hospital of Thessaloniki "G. Papanikolaou"

Thessaloniki, Greece, 57010

Actively Recruiting

12

A.O.U.C Policlinico di Bari

Bari, Italy, 70124

Actively Recruiting

13

AOU Policlinico Rodolico San Marco

Catania, Italy, 95125

Actively Recruiting

14

Azienda Ospedale Universita Padova

Padova, Italy, 35128

Not Yet Recruiting

15

University of Padova

Treviso, Italy, 31122

Actively Recruiting

16

Pomorski Uniwersytet Medyczny

Szczecin, Poland, 71252

Actively Recruiting

17

Spitalul Clinic Colentina

Bucharest, Romania, 020125

Not Yet Recruiting

18

Institutul Clinic Fundeni

Bucharest, Romania, 22328

Not Yet Recruiting

19

Institutul Oncologic Prof. Dr. Ion Chiricuta Cluj-Napoca

Cluj-Napoca, Romania, 400015

Not Yet Recruiting

20

Spitalul Clinic Municipal Filantropia Craiova

Craiova, Romania, 200143

Not Yet Recruiting

21

Hospital Clinico San Carlos

Madrid, Spain, 28040

Actively Recruiting

22

Hospital Universitario 12 de Octubre

Madrid, Spain, 28041

Actively Recruiting

23

Hospital Universitari Son Espases

Palma, Spain, 70120

Actively Recruiting

24

Lund University Hospital

Lund, Sweden, SE-221 85

Not Yet Recruiting

25

Ankara University Medical Faculty

Ankara, Turkey (Türkiye), 06100

Actively Recruiting

26

Antalya Training and Research Hospital

Antalya, Turkey (Türkiye), 7100

Actively Recruiting

27

Istanbul Universitesi

Istanbul, Turkey (Türkiye), 34098

Not Yet Recruiting

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Research Team

T

Takeda Contact

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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