Actively Recruiting

Phase Not Applicable
Age: 18Years - 30Years
All Genders
Healthy Volunteers
NCT05595434

Reality-monitoring & Stress

Led by Hôpital le Vinatier · Updated on 2025-07-24

40

Participants Needed

1

Research Sites

81 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Reality-monitoring is a crucial cognitive process in daily life to remember the source of an information. Deficits of reality-monitoring have been shown into the continuum of schizophrenia, suggesting a preexisting alteration in population at-risk for psychosis that will be exacerbated during psychotic transition. It is admitted that stress plays a crucial role in the psychotic transition and can alter cognitive performances. However, less is known about the effects of stress on reality-monitoring, even though this process appears to be central in psychotic disorders. The aim of this project is to investigate the effect of stress on reality-monitoring, both on behavioral and neurophysiological aspects

CONDITIONS

Official Title

Reality-monitoring & Stress

Who Can Participate

Age: 18Years - 30Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Right-handed men and women aged between 18 and 30
  • Provided written informed consent
  • Women must be using oral contraceptives
  • French speakers and readers
Not Eligible

You will not qualify if you...

  • Do not consent to participate
  • Smokers
  • Night shift workers
  • Visual or hearing impairments that interfere with reading or listening tasks
  • Taking any medication except oral contraceptives
  • Having neurological, hormonal, or blood circulation diseases (e.g., Raynaud's disease)
  • Personal or first-degree family history of diagnosed psychiatric disorders (per DSM-5 criteria)
  • Psychotic prodrome symptoms with a score above 6 on the PQ-16 questionnaire
  • Regularly practicing a musical instrument
  • Pregnant or nursing

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Centre Hospitalier le Vinatier

Bron, France, 69678

Actively Recruiting

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Research Team

S

SARTLET Lydie

CONTACT

M

Mondino Marine, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

BASIC_SCIENCE

Number of Arms

2

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