Actively Recruiting
RealMove (Lung): Assessing Tumour Motion With Dynamic MRI
Led by Region Stockholm · Updated on 2025-09-02
150
Participants Needed
1
Research Sites
626 weeks
Total Duration
On this page
Sponsors
R
Region Stockholm
Lead Sponsor
U
Uppsala University Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
The study aims to develop an improved method to tailor the geometric safety margin when treating with stereotactic body radiotherapy (SBRT), to avoid tumour cells being missed during irradiation and to limit the exposure of normal tissues as much as possible. Dynamic magnetic resonance imaging (MRI) is assumed to represent the tumour motion during the respiratory cycle more realistically, compared to 4-dimensional computed tomography (4D CT), thanks to its high temporal resolution and the possibility to image the motion over a longer period of time. Patients receiving SBRT for a pulmonary target located below the level of the carina are included in the study, and the hypothesis will be tested through a comparison of the tumour amplitude measured with each modality. Furthermore, the predictive value of the image series acquired at treatment planning, for the motion patterns observed at each treatment fraction, will be evaluated through repeated 4D CBCT acquisitions.
CONDITIONS
Official Title
RealMove (Lung): Assessing Tumour Motion With Dynamic MRI
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Accepted for stereotactic body radiotherapy treatment of one or more lung targets located below the carina
- Age 18 years or older
- Able to maintain an immobilized position for at least 30 minutes
- Adequate Swedish language skills and cognitive function to understand study information and complete questionnaires
You will not qualify if you...
- Pregnancy or breastfeeding, or planning pregnancy or breastfeeding during treatment
- Contraindications for MRI examination
- Unable to participate in the study for other reasons
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Karolinska University Hospital
Stockholm, Sweden, 17176
Actively Recruiting
Research Team
M
Mattias Hedman, MD PhD
CONTACT
E
Eva Onjukka, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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