Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
NCT07352475

Reasoning Enrichment With Feedback From IA in NEphrology Trial

Led by University Hospital, Lille · Updated on 2026-01-20

100

Participants Needed

1

Research Sites

58 weeks

Total Duration

On this page

Sponsors

U

University Hospital, Lille

Lead Sponsor

I

Institut Pasteur de Lille

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this clinical trial is to learn how artificial intelligence (AI) may help doctors make diagnoses in kidney medicine. The researchers want to know whether an AI tool called a large language model (LLM) can help doctors choose the correct diagnosis more often and feel more confident in their answers. Before starting the study, the research team tested several AI models and chose one of the best performers, a GPT-5-class model set to use high reasoning effort. The main questions this study aims to answer are: 1. Do doctors make more correct diagnoses when they can see AI suggestions? 2. Does seeing AI suggestions change how confident doctors feel about their diagnosis? Researchers will compare doctors who receive AI suggestions with doctors who do not receive AI suggestions to see how the AI affects accuracy, confidence, and decision-making. Participants will complete up to 10 online clinical cases. For each case, they will: 1. Read a short medical scenario 2. Suggest up to three possible diagnoses (If in the AI group) Review the AI's suggestions and decide whether to change their answer The study will also look at how long participants take to answer each case and how the AI's performance compares to the human answers.

CONDITIONS

Official Title

Reasoning Enrichment With Feedback From IA in NEphrology Trial

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 years or older.
  • Able to read and answer clinical vignettes in English or French.
  • Access to a computer or smartphone with an internet connection.
  • Provides informed consent online.
  • Expected to have at least basic medical training (medical students, residents, fellows, or practicing clinicians), although no formal verification is required.
Not Eligible

You will not qualify if you...

  • Individuals under 18 years of age.
  • Unable to complete online study procedures.
  • Prior involvement in design, development, or evaluation of the AI system used in this study.

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Lille University Hospital (online study)

Lille, France, 59000

Actively Recruiting

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Research Team

R

Raphaël BENTEGEAC, MD, MPH

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

DIAGNOSTIC

Number of Arms

2

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