Actively Recruiting

Phase Not Applicable
Age: 20Years - 80Years
All Genders
NCT06031623

REBOA in Nontraumatic OHCA

Led by Seoul National University Hospital · Updated on 2025-01-28

234

Participants Needed

1

Research Sites

154 weeks

Total Duration

On this page

Sponsors

S

Seoul National University Hospital

Lead Sponsor

F

Far Eastern Memorial Hospital

Collaborating Sponsor

AI-Summary

What this Trial Is About

The investigators propose a multicenter randomized controlled trial in South Korea and Taiwan to observe the clinical effects of REBOA on nontraumatic out-of-hospital-cardiac-arrest (OHCA) patients. While REBOA has been traditionally used in trauma for hemorrhage control, it has also shown promising results in nontraumatic cardiac arrests by rerouting circulation to increase perfusion in the coronary and brain.

CONDITIONS

Official Title

REBOA in Nontraumatic OHCA

Who Can Participate

Age: 20Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult nontraumatic out-of-hospital cardiac arrest (OHCA)
  • Witnessed cardiac arrest
  • Arrival at emergency room from 9 AM to 5 PM in South Korea or 8 AM to 8 PM in Taiwan
  • Age between 20 and 80 years old
Not Eligible

You will not qualify if you...

  • Age below 20 years or over 80 years
  • Traumatic cardiac arrest
  • Unwitnessed cardiac arrest
  • Pregnancy
  • Achieved return of spontaneous circulation (ROSC) upon emergency department arrival
  • Pre-cardiac arrest cerebral performance category of 3-4
  • Evidence of cardiac arrest due to bleeding such as gastrointestinal bleeding
  • Suspected or known aortic disease including dissection, intramural hematoma, or aneurysm
  • Legal representative requested termination of resuscitation before enrollment
  • Declared dead at the scene before randomization
  • Meeting criteria for extracorporeal cardiopulmonary resuscitation (ECPR) and decision to perform ECPR

AI-Screening

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Trial Site Locations

Total: 1 location

1

Seoul National Univeristy Bundang Hospital

Seongnam-si, Gyeonggi-do, South Korea, 13620

Actively Recruiting

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Research Team

H

Hee Eun Kim

CONTACT

D

Dong Hyun Jang

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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