Actively Recruiting
R.E.C.K vs Exparel in Robotic Nephrectomy
Led by Wake Forest University Health Sciences · Updated on 2026-01-20
170
Participants Needed
1
Research Sites
98 weeks
Total Duration
On this page
Sponsors
W
Wake Forest University Health Sciences
Lead Sponsor
A
Atrium Health Levine Cancer Institute
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of the study is to evaluate the efficacy of R.E.C.K (ropivacaine epinephrine clonidine ketorolac) vs Exparel during robotic partial and radical nephrectomy in a single institution, prospective, randomized trial. The study will evaluate post operative Numerical Rating Score (NRS) pain scores, post operative pain medication intake (opioids and over-the-counter pain medicines) and length of stay across the two patient cohorts. The findings will help to inform whether the increased cost of Exparel when compared to R.E.C.K is justified.
CONDITIONS
Official Title
R.E.C.K vs Exparel in Robotic Nephrectomy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Ability to understand and willing to sign an IRB-approved informed consent
- Age 18 years or older at time of consent
- Planned robotic partial or radical nephrectomy
You will not qualify if you...
- Not a candidate to receive R.E.C.K or Exparel as determined by the enrolling investigator
- Known pregnancy
- Chronic opioid use within 30 days prior to randomization (defined as 30 MME/day or more)
- Uncontrolled illness such as active infection, symptomatic heart failure, unstable angina, cardiac arrhythmia, or psychiatric/social issues limiting study compliance
- Known allergy to R.E.C.K and/or Exparel
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Levine Cancer
Charlotte, North Carolina, United States, 28204
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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