Actively Recruiting

Phase 1
Age: 18Years - 80Years
MALE
NCT04186585

Recommended Dose Estimation of BP-C2

Led by Meddoc · Updated on 2025-05-09

8

Participants Needed

1

Research Sites

130 weeks

Total Duration

On this page

Sponsors

M

Meddoc

Lead Sponsor

M

Meabco A/S

Collaborating Sponsor

AI-Summary

What this Trial Is About

The aim is to estimate an oral administered recommended dose of BP-C2 in addition to hormone treatment of prostate cancer. The study population consists of prostatic cancer patients between 18 and 80 years of age undergoing hormonal treatment. Four patients will be recruited consecutively from each of two participating hospital. The study will be performed as an open, one-dimensional multi-center trial with a 3-level within-patient Response Surface Pathway (RSP) design.

CONDITIONS

Official Title

Recommended Dose Estimation of BP-C2

Who Can Participate

Age: 18Years - 80Years
MALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Prostate cancer patients between 18 and 80 years of age under hormonal treatment
Not Eligible

You will not qualify if you...

  • Patients with expected survival time below 3 months
  • Abnormal liver function classified as total bilirubin >34 �b5mol/l or ALAT > 3 times the upper normal range (ULN). In case of metastases in the liver, the ALAT limit for exclusion is set to 5 x ULN.
  • Abnormal kidney function defined by serum creatinine >120 �b5mol/l.
  • Patients with verified metastasis to the brain.
  • Synchronous cancer except for non-melanoma skin cancer and early stage of cervical cancer.
  • Clinically significant abnormal ECG.
  • Under radiological therapy
  • Under systemic treatment with corticosteroids or other immunosuppressive drugs the last 3 weeks before start of the trial treatment.
  • Participating in another clinical trial with pharmaceuticals the last six weeks before start of this trial treatment.
  • Not able to understand information.
  • Do not want or not able to give written consent to participate in the study.

AI-Screening

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Trial Site Locations

Total: 1 location

1

Meddoc

Skjetten, Akershus, Norway, 2013

Actively Recruiting

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Research Team

S

Stig Larsen, Phd

CONTACT

H

Henning Arboe, MSc

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

OTHER

Number of Arms

3

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Recommended Dose Estimation of BP-C2 | DecenTrialz