Actively Recruiting

Age: 18Years +
All Genders
ID06774755

Reconstructions of Chest Wall Defects: a Retrospective Study Evaluating Diagnostic and Therapeutic Approaches in Complex Thoracic Reconstruction Sponsored by IRCCS Azienda Ospedaliero-Universitaria di Bologna

Led by IRCCS Azienda Ospedaliero-Universitaria di Bologna · Updated on 2025-01-14

100

Participants Needed

1

Research Sites

160 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to identify the best diagnostic and therapeutic approaches for patients with complex chest wall defects, including those requiring thoracic and sternal reconstruction. It addresses the challenges posed by patients who often have multiple health issues like obesity, diabetes, cardiovascular, and respiratory diseases, which can affect surgical outcomes. The study also seeks to improve multidisciplinary management through retrospective analysis of past cases to develop optimized therapeutic protocols. The study reviews different surgical and medical treatment options used in complex chest wall reconstructions and sternal wound treatments, noting the lack of universally accepted guidelines. It focuses on analyzing past interventions performed at the AOU Sant'Orsola (now IRCCS), assessing choices made during the demolitive, reconstructive, and pharmacological phases. The goal includes creating algorithms to guide surgical and medical decisions to enhance problem resolution, reduce hospital stays, and improve quality of life. Participants' clinical progress and outcomes from thoracic and sternal reconstruction surgeries will be retrospectively evaluated. The study involves reassessing diagnostic and therapeutic decisions to measure technical success and patient responses. Spirometric evaluations and stabilization of comorbid conditions prior to surgery are important considerations. The research covers up to the 100th patient enrolled and aims to support better multidisciplinary care for these complex cases.

CONDITIONS

Official Title

Reconstructions of Chest Wall Defects: a Retrospective Study

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • All patients undergoing sternal or thoracic reconstruction in collaboration or not with the Reconstructive Plastic Surgery Unit
  • Obtaining informed consent
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

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Trial Site Locations

Total: 1 location

1

IRCCS AOU di Bologna Policlinico di Sant'Orsola

Bologna, Italy, 40138

Actively Recruiting

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Research Team

M

Marco Pignatti, MD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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