Actively Recruiting
Recording of Intraoperative Spinal Cord Stimulation and Monitoring
Led by University of California, Los Angeles · Updated on 2025-03-10
150
Participants Needed
1
Research Sites
835 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Opioid overdose suppresses brainstem respiratory circuits, causes apnea, and may result in death. Epidural electrical stimulation (EES) at the cervical spinal cord facilitated motor activity in rodents and humans, and we hypothesized that EES of the cervical spinal cord could antagonize opioid-induced respiratory depression in humans. In this study, we will stimulate the spinal cord during surgery and assess its effects on respiratory function in human patients.
CONDITIONS
Official Title
Recording of Intraoperative Spinal Cord Stimulation and Monitoring
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Any patients undergoing brain or spinal cord surgery where spinal neuromonitoring is utilized.
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of California, Los Angeles
Los Angeles, California, United States, 90095
Actively Recruiting
Research Team
D
Daniel Lu, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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