Actively Recruiting
Recovery of Consciousness Following Intracerebral Hemorrhage
Led by Columbia University · Updated on 2026-05-13
150
Participants Needed
2
Research Sites
615 weeks
Total Duration
On this page
Sponsors
C
Columbia University
Lead Sponsor
P
Pitié-Salpêtrière Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
The objectives of the RECONFIG clinical study are to : 1. To identify the time to the first diagnosis of cognitive motor dissociation (CMD) in intracerebral hemorrhage (ICH) patients and to investigate whether these patients will clinically follow commands earlier after the hemorrhage. 2. To determine whether CMD independently predicts long term functional outcomes (6-month mRS scores) in ICH patients, and is associated with long term cognitive and quality of life outcomes. 3. To determine the EEG response to verbal commands of the motor imagery paradigm between patients with and without sensory aphasia. The overall goal is to determine predictors and the trajectory of neurological recovery.
CONDITIONS
Official Title
Recovery of Consciousness Following Intracerebral Hemorrhage
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 years or older
- Diagnosis of primary intracerebral hemorrhage confirmed by Head CT and/or MRI in the frontal lobe, thalamus, or striatocapsular region
- Unresponsive to commands within 48 hours after onset of the bleed
- English, Spanish, or French as the primary language
You will not qualify if you...
- Major bleeding in the cortex outside of the frontal lobe, cerebellum, or brainstem deemed cause of unconsciousness
- Other causes of intracerebral hemorrhage or different types of acute brain injury such as traumatic brain injury
- Severe cardiorespiratory compromise or other life-threatening conditions at enrollment
- Evidence of pre-existing aphasia or deafness
- Unconscious before the intracerebral hemorrhage
- Pregnancy
- Prisoners
- Health care proxy declines participation or chooses withdrawal of life-sustaining therapies
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
University of Miami and Jackson Health System (UM/JHS)
Miami, Florida, United States, 33136
Actively Recruiting
2
Columbia University Medical Center
New York, New York, United States, 10032
Actively Recruiting
Research Team
J
Jan Claassen, MD
CONTACT
A
Angela Velazquez, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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