Actively Recruiting
The Recovery in Stroke Using PAP Study
Led by Yale University · Updated on 2025-09-05
360
Participants Needed
1
Research Sites
317 weeks
Total Duration
On this page
Sponsors
Y
Yale University
Lead Sponsor
H
Hartford HealthCare
Collaborating Sponsor
AI-Summary
What this Trial Is About
The proposed study is a randomized controlled trial among an anicipated 180 participants with acute ischemic stroke and mod/severe OSA diagnosed by ambulatory polysomnography (PSG) comparing PAP treatment with usual care concerning the primary outcome of functional recovery.
CONDITIONS
Official Title
The Recovery in Stroke Using PAP Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Have an acute ischemic stroke confirmed by brain imaging within 48 hours of symptom onset
- Be within 5 days of neurologic symptoms onset
- Have moderate (AHI 15 to less than 30) or severe (AHI 30 or higher) obstructive sleep apnea (OSA) with an apnea-hypopnea index (AHI) of 15 or more
You will not qualify if you...
- Past use of prescribed positive airway pressure (PAP) treatment for OSA
- Suspected sleep disorder other than OSA (e.g., narcolepsy)
- Life expectancy less than 6 months (e.g., hospice patients)
- Require mechanical ventilation
- Non-English speaking patients
- Central sleep apnea with more than 50% of respiratory events classified as central apnea
- Resting oxygen saturation below 90%
- Inability to provide own informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Yale University
New Haven, Connecticut, United States, 06519
Actively Recruiting
Research Team
R
Radu Radulescu, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
4
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