Actively Recruiting
Recovery Times of Half Dose Sugammadex and Neostigmine for Rocuronium-induced Neuromuscular Blockade
Led by Universitas Padjadjaran · Updated on 2025-01-28
60
Participants Needed
1
Research Sites
12 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
In operating procedure with general anesthesia muscle relaxant is usually used to increase success rate of the operation and to give better outcome. The use of reversal drugs aims to reduce the risk of post-operative complications due to muscle relaxants. Neostigmine is commonly used as a reversal drug, but its indirect mechanism of action results in a long and unpredictable recovery time. Sugammadex directly bind and inactivate rocuronium, in which resulting in a faster and predictable recovery time. However, the high price limits the use of sugammadex. This study aims to compare the effect of half dose sugammadex and neostigmine against the moderate neuromuscular blockade of rocuronium. The main questions it aims to answer are: Does half dose sugammadex gives faster recovery time? Researchers will compare sugammadex to neostigmine to see if sugammadex gives faster recovery time. Participants will: Be given sugammadex or neostigmine as a reversal drug after the operation done
CONDITIONS
Official Title
Recovery Times of Half Dose Sugammadex and Neostigmine for Rocuronium-induced Neuromuscular Blockade
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients who underwent laparoscopic cholecystectomy under general anesthesia
- Using muscle relaxant rocuronium
- Aged 18-59 years
- American Society of Anesthesiologists (ASA) physical status classification of 1 or 2
You will not qualify if you...
- History of drug allergies to the agents used
- Renal dysfunction
- Musculoskeletal disorders
- Central nervous system disorders
- Difficult airways requiring intubation without the use of muscle relaxants
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Hasan Sadikin General Hospital
Bandung, West Java, Indonesia, 40161
Actively Recruiting
Research Team
R
Rivan P Rivan Putra Afewa, M.D., M.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here