Actively Recruiting

Age: 18Years +
All Genders
NCT04460859

RecruitmEnt Assessed by eleCtRical Impedance Tomography

Led by Unity Health Toronto · Updated on 2025-05-20

171

Participants Needed

4

Research Sites

364 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The RECRUIT study is a multinational, multicenter physiological observational study conducted by the PLUG working group. It is a single-day study (1.5-2 hours) associated with specific lung (de)recruitment maneuvers to verify the feasibility of measuring the potential for lung recruitment in mechanically ventilated patients with ARDS by electrical impedance tomography (EIT).

CONDITIONS

Official Title

RecruitmEnt Assessed by eleCtRical Impedance Tomography

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Intubated patients with moderate to severe ARDS according to the Berlin definition (PaO2/FiO2 ratio ≤ 200 mmHg)
  • Under continuous sedation with or without paralysis
Not Eligible

You will not qualify if you...

  • Age under 18 years
  • Presence of bronchopleural fistula
  • Pure COPD exacerbation
  • Contraindications to EIT monitoring such as burns, pacemaker, or thoracic wounds limiting electrode placement
  • Hemodynamic instability defined as systolic blood pressure < 75 mmHg or mean arterial pressure < 60 mmHg despite vasopressor use and/or heart rate < 55 bpm
  • Attending physician considers transient high airway pressure unsafe

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 4 locations

1

Faculdade de Medicina da University São Paulo

São Paulo, Brazil

Actively Recruiting

2

St. Michael's Hospital

Toronto, Ontario, Canada, M5B1T8

Actively Recruiting

3

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico

Milan, Italy

Not Yet Recruiting

4

Vall d'Hebron University Hospital

Barcelona, Spain

Actively Recruiting

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Research Team

L

Laurent Brochard, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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