Evaluation of Recruitment Maneuvers and Personalized Electrical Impedance Tomography-Guided PEEP During Abdominal Laparoscopic Surgery to Improve Lung Function and Gas Exchange

What this Trial Is About

Researchers are evaluating the effects of recruitment maneuvers and personalized positive end-expiratory pressure PEEP guided by electrical impedance tomography EIT compared to conventional ventilation in adult patients undergoing abdominal laparoscopic surgery. The study aims to improve regional lung ventilation, gas exchange, and pulmonary mechanics while reducing postoperative pulmonary complications such as atelectasis, which can impair breathing after surgery. Participants are randomized into two groups. The intervention group receives intraoperative recruitment maneuvers and PEEP adjusted using EIT with a stepwise decremental PEEP trial, starting at 5 cm H2O and increasing up to 20 cm H2O during pressure-controlled ventilation. The control group receives constant PEEP of 5 cm H2O without recruitment maneuvers during ventilation. Both groups receive volume-controlled ventilation with standardized tidal volumes and respiratory settings to maintain oxygen saturation and normal carbon dioxide levels. During the study, participants undergo monitoring of lung ventilation distribution, oxygenation, and pulmonary mechanics during surgery and on the first postoperative day. Researchers also evaluate hemodynamic effects, lung injury events, and pulmonary complications for up to five days after surgery. The study includes safety protocols and allows adjustments if complications arise. Overall participation lasts through the surgical period and early postoperative recovery to assess lung function and clinical outcomes.

Recruitment Maneuvers and PEEP-guided Electrical Impedance Tomography for Abdominal Laparoscopic Surgery Patients