Actively Recruiting
Redesigning the Surgical Pathway (PROMoTE)
Led by Sunnybrook Health Sciences Centre · Updated on 2025-09-12
260
Participants Needed
1
Research Sites
207 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Cognitive complications, that is problems with thinking and memory, are incredibly common after surgery, occurring in 10-50% of all older surgical patients. These complications can take different forms, but one of the most common is postoperative delirium (POD), a short-term state of confusion. In addition to being stressful for patients and their families, POD is linked to longer hospital stays, increased costs, higher mortality rates and other problems after surgery. Despite this, POD is often not recognized by doctors and there are currently no effective medications to treat POD. However, simple strategies such as helping patients to sleep properly and remain hydrated, have been shown to help. This study is testing if a delirium-reduction program will reduce postoperative delirium (POD) in older surgical patients. The investigators will first test memory and thought processes before surgery to find people who are most likely to develop POD. Once these people have been identified, they will be enrolled in a program which includes recommendations for their care team (e.g. surgeon, anesthesiologist, nurses) as well as educational materials for them and their family related to things that can be done to prevent delirium. By identifying at-risk patients and making sure that their doctors and caregivers are aware of how to prevent delirium, the investigators expect that this study will make surgery safer for older surgical patients.
CONDITIONS
Official Title
Redesigning the Surgical Pathway (PROMoTE)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 60 years old or older
- Undergoing major elective surgery with an expected hospital stay of at least one night
- Evidence of cognitive impairment on baseline screening tests (score less than 90 on CBB or greater than 10 on S-OMCT)
You will not qualify if you...
- Undergoing cardiac surgery
- Undergoing intracranial neurosurgery
- Known substance use disorder declared by patient
- Unlikely to comply with study assessments (e.g., no fixed address or no access to internet/computer/phone)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Sunnybrook Health Sciences Centre
Toronto, Ontario, Canada
Actively Recruiting
Research Team
S
Stephen Choi, MD, MSc
CONTACT
L
Lilia Kaustov, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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