Actively Recruiting

Phase Not Applicable
Age: 60Years +
All Genders
NCT05114876

Redesigning the Surgical Pathway (PROMoTE)

Led by Sunnybrook Health Sciences Centre · Updated on 2025-09-12

260

Participants Needed

1

Research Sites

207 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Cognitive complications, that is problems with thinking and memory, are incredibly common after surgery, occurring in 10-50% of all older surgical patients. These complications can take different forms, but one of the most common is postoperative delirium (POD), a short-term state of confusion. In addition to being stressful for patients and their families, POD is linked to longer hospital stays, increased costs, higher mortality rates and other problems after surgery. Despite this, POD is often not recognized by doctors and there are currently no effective medications to treat POD. However, simple strategies such as helping patients to sleep properly and remain hydrated, have been shown to help. This study is testing if a delirium-reduction program will reduce postoperative delirium (POD) in older surgical patients. The investigators will first test memory and thought processes before surgery to find people who are most likely to develop POD. Once these people have been identified, they will be enrolled in a program which includes recommendations for their care team (e.g. surgeon, anesthesiologist, nurses) as well as educational materials for them and their family related to things that can be done to prevent delirium. By identifying at-risk patients and making sure that their doctors and caregivers are aware of how to prevent delirium, the investigators expect that this study will make surgery safer for older surgical patients.

CONDITIONS

Official Title

Redesigning the Surgical Pathway (PROMoTE)

Who Can Participate

Age: 60Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • 60 years old or older
  • Undergoing major elective surgery with an expected hospital stay of at least one night
  • Evidence of cognitive impairment on baseline screening tests (score less than 90 on CBB or greater than 10 on S-OMCT)
Not Eligible

You will not qualify if you...

  • Undergoing cardiac surgery
  • Undergoing intracranial neurosurgery
  • Known substance use disorder declared by patient
  • Unlikely to comply with study assessments (e.g., no fixed address or no access to internet/computer/phone)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Sunnybrook Health Sciences Centre

Toronto, Ontario, Canada

Actively Recruiting

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Research Team

S

Stephen Choi, MD, MSc

CONTACT

L

Lilia Kaustov, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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