Actively Recruiting

Age: 40Years - 70Years
All Genders
NCT06949722

Redirecting Poor Sleep Drivers of Early Cardiovascular Disease

Led by National University of Singapore · Updated on 2025-04-29

1500

Participants Needed

1

Research Sites

140 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Sleep health is a critical component of cardiovascular well-being, and poor sleep has been linked with increased risk for all-cause mortality including cardiovascular disease (CVD). Moreover, many individuals within a population may have underlying, subclinical cardiovascular conditions, such as hypertension and arterial stiffness, and these may risk progressing to advanced CVD when coupled with inadequate sleep duration and quality. Given that Singapore ranks as the third most sleep-deprived city globally, understanding the relationship between sleep health and the prevalence and progression of CVD becomes increasingly important for population health. In addition, depression and psychological stress could also lead to poorer cardiovascular health by increasing blood cholesterol, blood sugar and blood pressure, and could also be directly related to or arise as a result of poor sleep. The aim of the current study is to track sleep and mental health using a combination of objective sleep tracking (Oura ring) and smartphone-based questionnaires (EMA), and examine their associations with detailed cardiovascular health data collected by the project RESET (Redirecting Immune, Lipid and Metabolic Drivers of Early Cardiovascular Disease).

CONDITIONS

Official Title

Redirecting Poor Sleep Drivers of Early Cardiovascular Disease

Who Can Participate

Age: 40Years - 70Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Willing to wear a ring
  • Have any of the following conditions: high blood pressure, high cholesterol, fatty liver, family history of heart diseases or stroke, obesity
Not Eligible

You will not qualify if you...

  • Prior history of heart attack or stroke or balloon angioplasty/stent placement
  • Restricted peripheral circulation (e.g., Raynaud's disease)
  • Pacemakers

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

National University of Singapore

Singapore, Singapore, 119077

Actively Recruiting

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Research Team

J

Ju Lynn Ong, PhD

CONTACT

G

Gizem Yilmaz, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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