Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06353594

Reduced Stent Strategy Versus Conventional Percutaneous Coronary Revascularization in Patients Presenting With STEMI

Led by Jorge Sanz Sanchez · Updated on 2024-04-09

1272

Participants Needed

15

Research Sites

598 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The objective is to compare a reduced stent strategy based on drug-coated balloon (DCB) percutaneous coronary intervention (PCI) with conventional drug-eluting stent (DES) coronary revascularization in patients presenting with ST-segment myocardial infarction (STEMI). Randomization will be performed after successful culprit-lesion guidewire crossing and flow restoration. Random allocation in a 1:1 fashion to one of the following strategies: * Study group: reduced stent PCI strategy (DCB-based) * Control group: conventional PCI strategy (DES-based).

CONDITIONS

Official Title

Reduced Stent Strategy Versus Conventional Percutaneous Coronary Revascularization in Patients Presenting With STEMI

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients presenting with STEMI and indication to undergo pPCI.
Not Eligible

You will not qualify if you...

  • Life expectancy less than 1 year due to non-cardiac disease.
  • Inability to provide informed consent.
  • Cardiogenic shock.
  • Left ventricular ejection fraction less than 15%.
  • Left main disease.
  • Stent thrombosis.
  • Patients with prior bypass graft lesions requiring PCI (culprit or non culprit lesions).
  • Patients with chronic total occlusions.
  • Untreatable coronary disease.
  • Non-identified culprit lesion.
  • Known allergy to aspirin, ticagrelor, prasugrel, clopidogrel, paclitaxel or sirolimus.

AI-Screening

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Trial Site Locations

Total: 15 locations

1

Hospital Universitario Y Politecnico La Fe

Valencia, Valencia, Spain

Actively Recruiting

2

Consorcio Hospitalario Provincial de Castellon

Castelló, Spain

Not Yet Recruiting

3

Hospital General Universitario de Elche

Elche, Spain

Not Yet Recruiting

4

Hospital Universitari de Bellvitge

L'Hospitalet de Llobregat, Spain

Not Yet Recruiting

5

Hospital Universitario 12 de Octubre

Madrid, Spain

Not Yet Recruiting

6

Hospital Universitario de La Princesa

Madrid, Spain

Not Yet Recruiting

7

Hospital Universitario Puerta de Hierro Majadahonda

Madrid, Spain

Not Yet Recruiting

8

Hospital Universitario Regional de Malaga

Málaga, Spain

Not Yet Recruiting

9

Hospital Universitario de Navarra

Pamplona, Spain

Not Yet Recruiting

10

Hospital Universitario Virgen Del Rocio

Seville, Spain

Not Yet Recruiting

11

Hospital Universitari Joan Xxiii de Tarragona

Tarragona, Spain

Not Yet Recruiting

12

Consorcio Hospital General Universitario de Valencia

Valencia, Spain

Actively Recruiting

13

Hospital Clinico Universitario de Valladolid

Valladolid, Spain

Not Yet Recruiting

14

Hospital Clinico Universitario Lozano Blesa

Zaragoza, Spain

Not Yet Recruiting

15

Hospital Universitario Miguel Servet

Zaragoza, Spain

Not Yet Recruiting

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Research Team

N

Naiara García Lamas

CONTACT

M

Marta Fernández Álvarez

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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