Actively Recruiting
Reducing African Americans' Alzheimer's Disease Risk Through Exercise (RAATE)"
Led by Pennington Biomedical Research Center · Updated on 2024-11-25
125
Participants Needed
1
Research Sites
377 weeks
Total Duration
On this page
Sponsors
P
Pennington Biomedical Research Center
Lead Sponsor
N
National Institute on Aging (NIA)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The RAATE proposal is designed to determine the effects of physical activity on risk factors for Alzheimer's Disease in older African American adults. The study will compare a physical activity program to an active control group. There are three main objectives of the protocol: 1) to determine if a physical activity intervention tailored to older African American adults is effective in modifying cognitive function associated with Alzheimer's Disease, 2) to determine if a physical activity intervention tailored to older African American adults is effective in modifying brain function and structure associated with Alzheimer's Disease, and 3) to determine if a physical activity promotion intervention tailored to African American adults is effective at enhancing physiological parameters. The primary endpoints for the study are episodic memory and executive functioning. The secondary outcomes include anthropometry, blood pressure, brain activation, cerebral blood flow, volume of whole brain and white matter hyperintensities, cardiorespiratory fitness, objectively measured physical activity, circulating hormones, and telomere length.
CONDITIONS
Official Title
Reducing African Americans' Alzheimer's Disease Risk Through Exercise (RAATE)"
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Self-identify as African American
- 60 years and older
- Willing to accept randomization
- Willing to attend group sessions
- No plans to move during the study period
- Free of conditions that make regular exercise unsafe (e.g., uncontrolled asthma, severe sickle cell disease)
- Not engaged in regular physical activity
- Short Physical Performance Battery score of 4 or higher
- Physically capable of exercise
You will not qualify if you...
- Cognitive impairment interfering with group participation
- Unwilling to give written informed consent
- Unable to attend group sessions
- Conditions preventing regular exercise
- Medical or principal investigator judgment warranting exclusion
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Pennington Biomedical Research Center
Baton Rouge, Louisiana, United States, 70808
Actively Recruiting
Research Team
M
Melissa Harris, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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