Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06806709

Reducing Blood Culture Contamination With the Use of a Needle-less Blood Draw Device (The PIVO Trial)

Led by The University of Queensland · Updated on 2026-02-04

1148

Participants Needed

4

Research Sites

71 weeks

Total Duration

On this page

Sponsors

T

The University of Queensland

Lead Sponsor

B

Becton, Dickinson and Company

Collaborating Sponsor

AI-Summary

What this Trial Is About

Blood cultures (BCs) are a blood test to look for an infection. Two problems with the sample collection are contamination by germs outside of the blood and not collecting enough blood in the tube, resulting in unusable samples. Many patients requiring a BC also have a peripheral intravenous catheter ("catheter") but these are not normally used for blood sampling. This means that patients receive many painful needles for both catheter insertion and blood sampling. There is a needle-free blood collection device (PIVO Pro) which can be used with a catheter to collect a blood sample. The goal of the PIVO Trial is to see if using the PIVO Pro for blood culture sample collection will have a lower amount of contamination than the usual method of blood sample collection. Patients 18 and older at 3 emergency departments will be included. Research nurses will look for patients in emergency who need a blood culture sample taken and they will be asked if they want to be involved in the trial. Half of the participants will use the PIVO Pro to take their blood sample and half will have the usual way of collecting blood. Participants do not have to do anything specifically for the trial. Information about the blood collection and results of the blood culture will be collected from the medical records and recorded for the trial.

CONDITIONS

Official Title

Reducing Blood Culture Contamination With the Use of a Needle-less Blood Draw Device (The PIVO Trial)

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Blood culture requested due to suspected bloodstream infection
  • Patients receiving a 22 gauge short peripheral intravenous catheter (or larger)
Not Eligible

You will not qualify if you...

  • Patients who have already commenced intravenous antimicrobial medications in the emergency department

AI-Screening

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Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 4 locations

1

Caboolture Hospital

Caboolture, Queensland, Australia, 4510

Actively Recruiting

2

Redcliffe Hospital

Redcliffe, Queensland, Australia, 4020

Actively Recruiting

3

Robina Hospital

Robina, Queensland, Australia, 4226

Actively Recruiting

4

The Gold Coast University Hospital

Southport, Queensland, Australia, 4215

Actively Recruiting

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Research Team

A

Andrea Valks

CONTACT

C

Claire Rickard

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

2

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