Using the Needle-Free PIVO Pro Device to Reduce Blood Culture Contamination in Adults A Randomized Study Comparing PIVO Pro With Standard Blood Collection Methods

What this Trial Is About

Researchers are evaluating the PIVO Pro needle-free blood collection device to reduce contamination in blood culture samples for patients suspected of bloodstream infection. This trial focuses on patients aged 18 and older who need blood culture tests in emergency departments. The goal is to compare contamination rates between the PIVO Pro device and the usual blood sampling methods, addressing issues like contamination and insufficient blood volume that affect test accuracy. Participants will be randomly assigned to either the PIVO Pro group or the control group using standard blood draw methods. The PIVO Pro device collects blood through a peripheral intravenous catheter by advancing a flexible tube beyond the catheter tip, aiming to obtain cleaner samples with less contamination. The control group will have blood drawn by usual methods like venepuncture or direct catheter draw. The trial includes an additional sub-study at one site examining catheter-related complications following blood draws. During the study, participants will receive standard care with no extra procedures required. Researchers will collect data on blood culture results, contamination rates, blood sample volume, and antibiotic use from medical records. Outcomes such as blood culture success without contamination and overall sample quality will be measured. The study will monitor participants for up to one week after blood collection to assess antibiotic use and catheter complications, ensuring safety and thorough evaluation over the trial period.

Reducing Blood Culture Contamination With the Use of a Needle-less Blood Draw Device (The PIVO Trial)