Actively Recruiting

Phase Not Applicable
Age: 50Years - 64Years
All Genders
Healthy Volunteers
NCT05522075

Reducing Blood Pressure in Mid-life Adult Binge Drinkers

Led by The University of Texas at Arlington · Updated on 2026-02-23

55

Participants Needed

1

Research Sites

179 weeks

Total Duration

On this page

Sponsors

T

The University of Texas at Arlington

Lead Sponsor

N

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study has two phases: Phase 1 is to examine blood pressure, microvascular function, and sympathetic nerve activity in mid-life adult binge drinkers vs. alcohol abstainers/moderate drinkers. Phase 2 is to examine the effect of 8-week aerobic exercise training on blood pressure, microvascular function, and sympathetic nerve activity in mid-life adult binge drinkers

CONDITIONS

Official Title

Reducing Blood Pressure in Mid-life Adult Binge Drinkers

Who Can Participate

Age: 50Years - 64Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Men and women aged 50 to 64 years who do not drink alcohol, drink moderately, or binge drink
  • Female participants must be postmenopausal (no menstrual periods for at least 1 year)
  • Participants must be able to speak and understand English
Not Eligible

You will not qualify if you...

  • History of diabetes, cardiovascular disease, liver disease, or kidney disease
  • Current or past smoking or illicit drug use
  • Blood pressure equal to or above 160/100 mm Hg
  • Obesity with BMI of 35 kg/m2 or higher
  • High cholesterol (total cholesterol over 230 mg/dl or LDL cholesterol over 160 mg/dl)
  • Active infection within the past 2 months
  • History of seizures, cancer, or inflammatory diseases like gout or rheumatoid arthritis
  • Unstable body weight with more than 5% change in the past 6 months
  • Regular aerobic exercise of 30 minutes at least 3 times per week
  • Current use of hormone replacement therapy such as estrogen, progesterone, or testosterone

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

University of Texas at Arlington

Arlington, Texas, United States, 76010

Actively Recruiting

Loading map...

Research Team

C

Chueh-Lung Hwang, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

3

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here