Actively Recruiting
Reducing Cognitive Impairment in Glioma with Repetitive Transcranial Magnetic Stimulation and Cognitive Strategy Training
Led by Linda Douw · Updated on 2024-11-18
16
Participants Needed
1
Research Sites
122 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The TRUE-GRIT study will assess the feasibility of a study protocol investigating the efficacy of a combination therapy consisting of cognitive strategy training (CST) and repetitive transcranial magnetic stimulation (rTMS) to reduce cognitive impairment in adult glioma patients. This study is part of the GRIP-project, a project aimed at investigating interventions for improving quality of life in brain tumor patients.
CONDITIONS
Official Title
Reducing Cognitive Impairment in Glioma with Repetitive Transcranial Magnetic Stimulation and Cognitive Strategy Training
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 years of age or older
- Histological diagnosis of diffuse glioma (WHO grade 2, 3, or 4)
- Subjective cognitive impairment with a CFQ-score of 44 or higher
- Able to give informed consent and undergo treatment and measurements
- Stable disease: no oncological treatment for 2 months prior to inclusion, no radiological progression on recent MRI (within 6 months), and no clinical progression at inclusion
- Stable dosage of anti-epileptic medication for at least 8 weeks
You will not qualify if you...
- Currently pregnant or gave birth less than three months ago
- Receiving other treatments for cognitive complaints
- Karnofsky performance score less than 70
- Tumor located in the parietal cortex
- Have implanted medical devices (e.g., pacemaker, deep brain stimulator, cochlear implants, medical infusion device)
- Presence of metal in the body
- Sleep deprivation
- Extreme claustrophobia or metallic objects in or on the body preventing MRI
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
VU University Medical Centers, location VUmc
Amsterdam, Netherlands, 1081 HV
Actively Recruiting
Research Team
M
Maxine Gorter, MSc
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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