Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
NCT05500963

Reducing Fatigue in People With Multiple Sclerosis by Treatment With TENS

Led by University of Colorado, Boulder · Updated on 2024-12-09

60

Participants Needed

1

Research Sites

292 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The objective of the randomized, sham-controlled trial will be to evaluate the effectiveness of treatment with transcutaneous electrical nerve stimulation (TENS) at reducing the level of fatigue experienced by people with MS.

CONDITIONS

Official Title

Reducing Fatigue in People With Multiple Sclerosis by Treatment With TENS

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Men and women 18-65 years old
  • Able to read, understand, and speak English to ensure safe participation
  • Clinical diagnosis of relapsing-remitting multiple sclerosis
  • Self-reported difficulty with walking
  • On stable doses of Ampyra, provigil, or other symptom-treating medications
  • No relapse or systemic steroids within the last 30 days
  • Able to arrange transportation to the Boulder campus
Not Eligible

You will not qualify if you...

  • Vision or hearing problems that have not been corrected
  • Problems with sensations to temperature, pressure, or pain
  • Any arm or leg problems that affect ability to hold a weight
  • Surgery to the arms or legs that continues to bother the participant
  • Metal implants
  • Medical conditions contraindicating exercise training such as major renal, pulmonary, hepatic, cardiac, gastrointestinal, HIV, cancer (except treated basal cell), other neurological disorders, or pregnancy
  • History of head injury or stroke
  • Taking antidepressants, anticholinergics, stimulants, sedatives, cannabis, illicit drugs, or medications for herpes or neurologic pain
  • Diagnosis of diabetes mellitus
  • Poorly controlled hypertension
  • History of seizure disorders
  • Drinking 2 or more alcoholic drinks per day or recent drug abuse (last 6 months)
  • Spasticity requiring activity changes more than once a week
  • Skin diseases or sensation problems in legs or hands impacting activities more than once a week
  • Unable to attend exercise sessions 3 days per week for 6 weeks

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Colorado

Boulder, Colorado, United States, 80309

Actively Recruiting

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Research Team

R

Roger Enoka, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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