Actively Recruiting

Phase 2
Age: 65Years +
All Genders
NCT06068543

Reducing Frailty for Older Cancer Survivors Using Supplements II

Led by University of Rochester · Updated on 2026-03-06

118

Participants Needed

1

Research Sites

322 weeks

Total Duration

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AI-Summary

What this Trial Is About

This study is a two-arm placebo controlled randomized clinical trial, to assess the effect of a 12-week EGCG intervention on physical frailty compared to placebo in pre-frail older cancer survivors.

CONDITIONS

Official Title

Reducing Frailty for Older Cancer Survivors Using Supplements II

Who Can Participate

Age: 65Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Be age 65 or over.
  • Be diagnosed with stage I-III cancer.
  • Have completed curative intent treatment 10 years or less before screening.
  • Patients on Anastrozole, Leuprolide acetate, or Bicalutamide endocrine therapies are allowed.
  • Have a Fried's Frailty Score of 1 or greater.
  • Able to provide informed consent.
Not Eligible

You will not qualify if you...

  • Have chemotherapy or other systemic cancer treatment planned during the study period.
  • Have abnormal liver function tests (ALT or AST over 3 times upper limit, bilirubin over 1.5 times upper limit) within 3 months.
  • Have uncontrolled or unmanaged liver disease.
  • Consume more than 6 cups of green tea per day.
  • Have known allergies to caffeine.
  • Have a major psychiatric illness requiring hospitalization within the last year.
  • Have been diagnosed with dementia.
  • Cannot provide informed consent due to lack of decision-making capacity as determined by the oncologist.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Rochester

Rochester, New York, United States, 14627

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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Reducing Frailty for Older Cancer Survivors Using Supplements II | DecenTrialz