Actively Recruiting

Phase Not Applicable
Age: 15Years +
All Genders
NCT07329166

Reducing Mobility-associated Interruption in HIV Treatment in Malawi

Led by University of California, Los Angeles · Updated on 2026-01-09

400

Participants Needed

1

Research Sites

58 weeks

Total Duration

On this page

Sponsors

U

University of California, Los Angeles

Lead Sponsor

P

Partners in Hope, Inc.

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this pilot clinical trial is to assess the feasibility and acceptability of an intervention package designed to reduce mobility-associated interruptions in HIV treatment in people living with HIV in Malawi who are initiating or returning to antiretroviral treatment (ART) after interruption. The main questions it aims to answer are: * Is the intervention acceptable to healthcare workers and ART clients? * Is the intervention feasible in the context of Malawi's health system, and what are the major operational challenges, resource requirements, and implementation barriers? In addition, researchers will compare HIV treatment outcomes (specifically ART retention rates) between intervention and control groups to establish a preliminary estimate of the intervention's efficacy. Participants will complete a survey on the day of enrollment and some participants will complete an in-depth interview and/or a survey after completion of the 6-month follow-up period. Facilities assigned to the intervention group will receive the full package of interventions (training on mobility-specific counseling for counsellors, access to a toll-free hotline for clients and healthcare workers, and training on multi-month dispensing for providers), while facilities assigned to the control group will provide standard of care.

CONDITIONS

Official Title

Reducing Mobility-associated Interruption in HIV Treatment in Malawi

Who Can Participate

Age: 15Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • 15 years of age or older
  • Living with HIV
  • Attending ART clinic to initiate ART for the first time, per self-report
  • Attending ART clinic to re-initiate care after missing a refill appointment by more than 28 days
Not Eligible

You will not qualify if you...

  • Attending ART clinic on behalf of someone else (guardian)
  • Attending ART clinic only to obtain an emergency refill
  • Attending ART clinic for routine refill without a recent interruption in treatment of 28 days or more
  • Transferring into study facility without a preceding treatment interruption of 28 days or more

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Partners in Hope

Lilongwe, Malawi

Actively Recruiting

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Research Team

M

Marguerite Thorp, MD, MPA/ID

CONTACT

K

Kathryn Dovel, PhD, MPH

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

HEALTH_SERVICES_RESEARCH

Number of Arms

2

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