Actively Recruiting

Phase 2
Age: 18Years - 64Years
All Genders
NCT05335070

Reducing Pain From Wisdom Molar Extractions

Led by Rutgers, The State University of New Jersey · Updated on 2025-12-05

20

Participants Needed

1

Research Sites

220 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a pilot study evaluating the ability of the Temporo-masseteric Nerve Block local anesthetic injection (this was called the Twin Block earlier) to reduce pain experienced by individuals undergoing removal of lower third molar(s) under intravenous sedation. Study participants will be queried for pain experience and pain medications taken during the first post-operative week and will present for a follow-up visit on Day 8.

CONDITIONS

Official Title

Reducing Pain From Wisdom Molar Extractions

Who Can Participate

Age: 18Years - 64Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older, up to 64 years
  • Any demographic
  • ASA physical status 1 or 2, meaning mild or no systemic illnesses and suitable for dental extraction under intravenous sedation
  • Not pregnant
  • Able to understand and provide informed consent
  • Has a smartphone and internet connection
Not Eligible

You will not qualify if you...

  • Age older than 64 years
  • Pregnant
  • Unable to provide informed consent
  • Any systemic condition increasing risk for complications under intravenous sedation
  • Allergy to dental local anesthetic
  • Cannot tolerate pain medications such as opioids, acetaminophen, or ibuprofen
  • Limited ability to open mouth adequately with or without pain

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

The University Hospital- Dental Clinic

Newark, New Jersey, United States, 07103

Actively Recruiting

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Research Team

G

Gayathri Subramanian, PhD, DMD

CONTACT

S

Samuel YP Quek, DMD, MPH

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

1

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