Actively Recruiting
Reducing Posttraumatic Stress Disorder (PTSD) Symptoms in First Responders and Frontline Health Care Workers
Led by University of Michigan · Updated on 2025-07-02
410
Participants Needed
12
Research Sites
171 weeks
Total Duration
On this page
Sponsors
U
University of Michigan
Lead Sponsor
N
National Institute of Mental Health (NIMH)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study addresses PTSD symptoms in First Responders and Healthcare workers. Specifically, it tests whether a brief PTSD treatment (talk therapy) effectively treats PTSD when provided to First Responders and Healthcare workers by counselors in Employee Assistance Programs (EAPs). The central hypothesis is that the PTSD treatment, Prolonged Exposure for Primary Care (PE-PC), will reduce PTSD symptoms and improve functioning, compared to EAP Treatment as Usual (TAU).
CONDITIONS
Official Title
Reducing Posttraumatic Stress Disorder (PTSD) Symptoms in First Responders and Frontline Health Care Workers
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Employed at an organization served by a participating Employee Assistance Program (EAP)
- Have a Post-Traumatic Stress Disorder Checklist for DSM-5 (PCL-5) score of 33 or higher
- Stable psychotropic medication use for at least 4 weeks
- For qualitative study: enrolled in the trial and identified as treatment responder or non-responder
You will not qualify if you...
- Severe cognitive impairment that likely prevents adherence to the study regimen
- High suicide risk as defined by study criteria
- Need for detoxification
- Active psychosis or unmanaged bipolar disorder
- Currently engaged in trauma-focused behavioral treatment (e.g., Prolonged Exposure or Cognitive Processing Therapy)
- Do not speak English
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 12 locations
1
Sharp Healthcare
San Diego, California, United States, 92129
Withdrawn
2
Tanner Health System
Carrollton, Georgia, United States, 30117
Actively Recruiting
3
University of Michigan
Ann Arbor, Michigan, United States, 48109
Actively Recruiting
4
Henry Ford Health System
Detroit, Michigan, United States, 48202
Active, Not Recruiting
5
Detroit Fire Department
Detroit, Michigan, United States, 48226
Actively Recruiting
6
Health Management Systems of America
Detroit, Michigan, United States, 48226
Actively Recruiting
7
Michigan State University
East Lansing, Michigan, United States, 48824-1037
Actively Recruiting
8
West Bloomfield Fire Department
West Bloomfield, Michigan, United States, 48322
Active, Not Recruiting
9
Cope NewYork-Presbyterian
New York, New York, United States, 10017
Actively Recruiting
10
University of Cincinati Health
Cincinnati, Ohio, United States, 45229
Not Yet Recruiting
11
ProMedica
Fremont, Ohio, United States, 43420
Actively Recruiting
12
Houston Fire Department
Houston, Texas, United States, 77002
Actively Recruiting
Research Team
J
James Garlick
CONTACT
N
Naomi Hemphill
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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