Actively Recruiting
Reducing the Risk of Chronic Hypertension and Improving Vascular Function Following Preeclampsia
Led by Medical College of Wisconsin · Updated on 2025-05-11
618
Participants Needed
2
Research Sites
244 weeks
Total Duration
On this page
Sponsors
M
Medical College of Wisconsin
Lead Sponsor
E
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The long-term goal of our work is to evaluate the effect of intensive postpartum blood pressure control on maternal cardiovascular health, risk of chronic hypertension, and reversal of vascular dysfunction generated by hypertensive disorders of pregnancy, thus attenuating the lifelong trajectory of cardiovascular disease risk.
CONDITIONS
Official Title
Reducing the Risk of Chronic Hypertension and Improving Vascular Function Following Preeclampsia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of hypertensive disorders of pregnancy including gestational hypertension, preeclampsia, eclampsia, or HELLP syndrome as per ACOG guidelines
- Postpartum between day 0 and day 4
- Age 18 years or older
- Able to communicate in English or Spanish
- Has an established obstetrician-gynecologist within the MCW or Northwestern University health system with access to electronic medical records
You will not qualify if you...
- Pre-existing hypertension before pregnancy
- Type 1 or type 2 diabetes mellitus
- Currently admitted to an intensive care unit at screening
- Diagnosis of hypertensive disorders of pregnancy made during postpartum readmission after initial hospital discharge
- Being discharged from hospital on the day of screening
- Known allergy or contraindication to nifedipine extended-release
- Unable or unwilling to provide informed consent
- Currently taking long-acting antihypertensive medication for routine care
- Maternal conditions affecting study outcomes such as sickle cell disease or systemic lupus erythematosus
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Northwestern University
Chicago, Illinois, United States, 60611
Actively Recruiting
2
Medical College of Wisconsin
Milwaukee, Wisconsin, United States, 53226
Actively Recruiting
Research Team
A
Alyssa M Hernandez, DO
CONTACT
A
Amandla Stanley, MSN
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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