Actively Recruiting
Reflectance Confocal Microscopy of Oral Cancers in Vivo: a Preliminary Trial Comparing Intra-oral Imaging With Pathology
Led by Memorial Sloan Kettering Cancer Center · Updated on 2026-03-16
140
Participants Needed
5
Research Sites
571 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to get images (pictures) of oral lesions, which occur inside the mouth, before the patient's surgery using a special camera. These pictures will be used in our research to evaluate a new technology that uses a laser and takes pictures of the microscopic structure of tissue. The technology is called "reflectance confocal microscopy." We would like to compare what the camera sees to biopsies (pathology) of the same area. We will evaluate the pictures obtained from the patient to determine whether this technology may be useful in the future. We hope this technology can be used as a tool for early diagnosis of oral cancers and for guiding surgery.
CONDITIONS
Official Title
Reflectance Confocal Microscopy of Oral Cancers in Vivo: a Preliminary Trial Comparing Intra-oral Imaging With Pathology
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with biopsy-proven oral squamous cell carcinoma scheduled for surgery in the MSK Head and Neck Service
- Ability to sign informed consent
- Age 18 years or older
You will not qualify if you...
- Cancer located in areas not convenient or accessible for imaging with the current RCM device, such as gingivobuccal region, back of the oral cavity, back of the tongue, floor of the mouth, or deep under the tongue
- Inability to give informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 5 locations
1
Memorial Sloan Kettering Basking Ridge (consent only)
Basking Ridge, New Jersey, United States
Actively Recruiting
2
Memorial Sloan Kettering Monmouth (consent only)
Middletown, New Jersey, United States, 07748
Actively Recruiting
3
Memorial Sloan Kettering West Harrison (consent only)
Harrison, New York, United States, 10604
Actively Recruiting
4
Memorial Sloan Kettering Cancer Center
New York, New York, United States, 10065
Actively Recruiting
5
Memorial Sloan Kettering Nassau (consent only)
Uniondale, New York, United States, 11553
Actively Recruiting
Research Team
S
Snehal Patel, MD
CONTACT
M
Milind Rajadhyaksha, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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