Actively Recruiting
Prognosis of Refractory Out-of-hospital Cardiac Arrests Treated With Extracorporeal Cardiopulmonary Resuscitation (ECMO) by the Urgent Medical Aid Service (SAMU) of Paris
Led by Assistance Publique - Hôpitaux de Paris · Updated on 2025-09-12
840
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
Sponsors
A
Assistance Publique - Hôpitaux de Paris
Lead Sponsor
U
URC-CIC Paris Descartes Necker Cochin
Collaborating Sponsor
AI-Summary
What this Trial Is About
Out-of-hospital cardiac arrest that does not regain spontaneous circulation despite advanced medical resuscitation is called refractory cardiac arrest. This research evaluates extracorporeal cardiopulmonary resuscitation (ECPR), a technique using an extracorporeal membrane oxygenation (ECMO) device to maintain organ perfusion while awaiting heart function recovery. Since 2011, the Paris SAMU has operated a specialized ECMO team for refractory cardiac arrests in Paris and surrounding areas, and this study aims to measure the real-life effectiveness of this approach over 20 years. The study involves patients aged over 18 who experience non-traumatic refractory cardiac arrest and receive or attempt ECMO treatment by the Paris SAMU ECMO team. Medical data will be collected prospectively for these patients during and after their hospital care, including intensive care unit stay and follow-up medical reports. The study focuses on long-term outcomes, including survival and cardiac function after ECMO treatment. Participants' data will be followed for one year after care to assess survival rates, neurological recovery, quality of life, heart function measured by left ventricular ejection fraction, occurrence of major cardiovascular events, and complications related to ECPR. Data is gathered from hospital records and communications with attending physicians. This observational study lasts 20 years, providing extensive monitoring of patient outcomes after refractory cardiac arrest treated with ECMO.
CONDITIONS
Brief Title
Refractory Cardiac Arrest Treated On Field By ECMO
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients who have received or attempted ECMO treatment after a non-traumatic refractory cardiac arrest by the Paris SAMU ECMO team during the study period
- Patients aged 18 years or older
- Non-opposition from the patient or a relative if the patient is deceased or unable to consent
You will not qualify if you...
- Patients under 18 years old
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 1 year after treatment
Participants who receive or attempt ECMO treatment after a refractory cardiac arrest are observed, with medical data collected during and after treatment to assess survival, neurological status, quality of life, cardiac function, and complications.
Data collected from hospital records and follow-up medical reports over 1 year
Trial Site Locations
Total: 1 location
1
Hôpital Necker-Enfants Malades
Paris, France, 75015
Actively Recruiting
Research Team
J
Jean-Herlé Raphalen, MD
H
Hélène Morel
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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