Actively Recruiting
Regeneration of Acutely Injured Nerves With Temporary Electrical Stimulation
Led by Epineuron Technologies Inc. · Updated on 2026-03-16
110
Participants Needed
15
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating a novel temporary peripheral nerve stimulation system to study its safety and effectiveness in helping regenerate acutely injured nerves. This study is designed to assess sensory recovery and monitor adverse events over a six-month period in adults with nerve injuries. The trial is randomized and double-blinded to compare the nerve stimulation device with a sham treatment. Participants will receive a single dose of electrical stimulation therapy lasting one hour, delivered by a single-use medical device placed near the injury site. The study groups include an active treatment group receiving the actual nerve stimulation and a sham group receiving a similar procedure without active stimulation. Both treatments are given once. Throughout the study, participants will be monitored for sensory recovery and any adverse effects at the six-month mark. The trial includes regular evaluations to track the progress of nerve regeneration and the safety of the device. The total participation period covers six months from treatment to final assessment.
CONDITIONS
Brief Title
Regeneration of Acutely Injured Nerves With Temporary Electrical Stimulation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Peripheral nerve injury
- Aged between 18 and 65 years
- All genders are eligible
You will not qualify if you...
- Peripheral neuropathy
- Presence of any active implanted medical device
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Single session
Participants receive a single, 1 hour dose of electrical stimulation or sham stimulation near the nerve injury site.
1 visit (in-person)
Duration - 6 months
Participants are monitored for sensory recovery and incidence of adverse events over 6 months.
Periodic follow-up visits during 6 months
Trial Site Locations
Total: 15 locations
1
University of Florida Health
Gainesville, Florida, United States, 32608
Actively Recruiting
2
Orlando Health Jewett Orthopedic Institute
Orlando, Florida, United States, 32806
Actively Recruiting
3
Louisiana State University Health Sciences Center
New Orleans, Louisiana, United States, 70112
Actively Recruiting
4
The Curtis National Hand Center
Baltimore, Maryland, United States, 21218
Completed
5
WellSpan Health
York, Pennsylvania, United States, 17403
Completed
6
John Peter Smith Hospital
Fort Worth, Texas, United States, 76104
Actively Recruiting
7
University of Alberta Hospital
Edmonton, Alberta, Canada
Completed
8
Saint John Regional Hospital
Saint John, New Brunswick, Canada
Actively Recruiting
9
Hamilton General Hospital
Hamilton, Ontario, Canada
Actively Recruiting
10
St. Joseph's Healthcare Hamilton
Hamilton, Ontario, Canada
Actively Recruiting
11
Roth | McFarlane Hand & Upper Limb Centre
London, Ontario, Canada
Active, Not Recruiting
12
Southlake Health
Newmarket, Ontario, Canada
Actively Recruiting
13
Humber River Health
Toronto, Ontario, Canada
Actively Recruiting
14
North York General Hospital
Toronto, Ontario, Canada
Actively Recruiting
15
Trillium Health Partners
Toronto, Ontario, Canada
Actively Recruiting
Research Team
T
Tracy Cameron, PhD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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