Actively Recruiting
Regime for Vitamin D Maintenance in Post-Operative Patients
Led by Sengkang General Hospital · Updated on 2026-05-04
100
Participants Needed
1
Research Sites
77 weeks
Total Duration
On this page
Sponsors
S
Sengkang General Hospital
Lead Sponsor
H
Hyphens Pharma Pte Ltd
Collaborating Sponsor
AI-Summary
What this Trial Is About
Vitamin D plays a significant part calcium and phosphate haemostasis, thus, intrinsically critical for bone health. Increasing evidence also reveal that insufficient serum vitamin D levels also result in poor muscle health with such individuals having a compromised muscle building potential (4 times slower muscle building). Muscle health is a critical component of a post-surgical patient recovery, with impaired muscle function leading to reduced functional ability, resulting in a poorer quality of life. Poor muscle health also has negative repercussion on survivability, with reduced overall, and disease-specific survival, especially shown in cancer patients. Thus, maintenance of vitamin D levels post-surgery may be more critical than previously thought.
CONDITIONS
Official Title
Regime for Vitamin D Maintenance in Post-Operative Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Serum 25-hydroxyvitamin D levels between 30-50 ng/ml at 4-6 weeks after operation
- Aged 21-65 years
- Ability to provide informed consent
- Willingness to take vitamin D supplements after surgery
- Willingness to have serum vitamin D levels checked periodically
You will not qualify if you...
- Underwent minor procedures (Table code <4a)
- History of chronic kidney disease or end-stage renal failure
- Previous history of ureteric or kidney stones
- Known hyperparathyroidism
- Non-ambulatory independently
- Known allergies to commercially available high-dose vitamin D formulations
- Vulnerable persons excluded from the study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Sengkang General Hospital
Singapore, Singapore, Singapore, 544886
Actively Recruiting
Research Team
F
Frederick H Koh, FRCS, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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