Actively Recruiting
Evaluation of the Effects of Regional Anesthesia Methods Applied in Total Knee Arthroplasty on Joint Range of Motion in the Postoperative Period and Patient Satisfaction
Led by Konya City Hospital · Updated on 2025-08-28
30
Participants Needed
1
Research Sites
1 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating how different regional anesthesia and pain relief methods affect knee movement and patient satisfaction after total knee replacement surgery. This randomized controlled trial includes 90 patients scheduled for elective total knee arthroplasty under spinal anesthesia. The study aims to compare three approaches to postoperative pain management and their impact on knee range of motion and patient experience. Participants will be randomly assigned to one of three groups: spinal anesthesia with an epidural catheter delivering bupivacaine, spinal anesthesia followed by an ultrasound-guided adductor canal catheter with continuous bupivacaine infusion, or spinal anesthesia combined with continuous intravenous tramadol infusion and additional rescue analgesia as needed. These treatments are applied after surgery, and the different methods are assessed over time. During the study, researchers will measure knee range of motion on postoperative days 1, 2, and 3, along with patient satisfaction scores. Additional evaluations include opioid use, Oxford Knee Score before surgery and 90 days after, pain levels using a visual analog scale, and monitoring for any anesthesia-related side effects for up to 90 days. The trial is conducted at a single center and is expected to be completed within six months.
CONDITIONS
Brief Title
Regional Anesthesia in TKA: Impact on Postoperative Joint Motion and Patient Satisfaction
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Scheduled for primary total knee arthroplasty
- Age 18 years or older
- American Society of Anesthesiologists (ASA) physical status I to III
- Accepting neuraxial anesthesia
You will not qualify if you...
- Skin infection at the planned injection site
- Sepsis
- Coagulopathy
- Refusal of neuraxial anesthesia
- Severe hypovolemia
- Demyelinating central nervous system disease
- Age under 18 years
- Illiterate in Turkish
- Non-cooperative patients
- Known allergy or hypersensitivity to bupivacaine
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 7 days post-surgery
Participants receive one of three regional anesthesia methods during total knee arthroplasty and postoperative analgesia to manage pain and improve knee motion.
Hospital stay with daily assessments on days 1, 3, and 7 after surgery
Duration - Up to 90 days post-surgery
Participants are assessed for longer-term outcomes including knee range of motion, patient satisfaction, opioid consumption, and adverse events.
Visits on postoperative day 90
Trial Site Locations
Total: 1 location
1
Yasin Tire
Konya, Meram, Turkey (Türkiye), 42140
Actively Recruiting
Research Team
Y
Yasin Tire
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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