Actively Recruiting
Regional Phenotyping of CF and Non-CF Bronchiectasis
Led by Children's Hospital Medical Center, Cincinnati · Updated on 2025-02-20
100
Participants Needed
1
Research Sites
320 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The Investigators propose to study pediatric subjects who are diagnosed with cystic fibrosis (CF) and patients with non-CF bronchiectasis, with the goal of developing markers of CF lung disease severity, progression, and therapy response. The Investigator's central hypothesis is that image-based markers can forecast pathophysiology prior to spirometric changes.
CONDITIONS
Official Title
Regional Phenotyping of CF and Non-CF Bronchiectasis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of cystic fibrosis based on sweat chloride >60 mMol/l
- Presence of two disease-causing CFTR mutations or end organ manifestations of cystic fibrosis
- Age 5 years or older
- Care provided by the CCHMC CF Care Center or other regional CF Care Centers if needed
- Healthy subjects 5 years or older with no known cardiopulmonary disease may be included for comparison
You will not qualify if you...
- Standard MRI exclusion criteria, including non-MRI-compatible metal implants or claustrophobia
- Pregnancy or lactation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Penny New
Cincinnati, Ohio, United States, 45229
Actively Recruiting
Research Team
P
Penny A New, BBA
CONTACT
C
Carrie Stevens, BS
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here