Actively Recruiting
A Registered Cohort Study on Brain Calcification
Led by Wan-Jin Chen · Updated on 2019-09-23
2000
Participants Needed
1
Research Sites
2608 weeks
Total Duration
On this page
Sponsors
W
Wan-Jin Chen
Lead Sponsor
T
Taipei Veterans General Hospital, Taiwan
Collaborating Sponsor
AI-Summary
What this Trial Is About
Brain calcification is a common finding seen in various conditions including metabolic, neurological, developmental disorders, infectious diseases, trauma, toxic exposures, and also in normal aging. Researchers aim to better understand the clinical and genetic features of brain calcification by following a group of people with this condition over time. This observational study is designed to gather long-term information about brain calcification and its hereditary aspects. Participants include patients who have brain calcium deposits confirmed by CT scans, their relatives, and unrelated healthy individuals. The study involves observing and collecting data without any treatment intervention. The cohort will be followed for up to 20 years to monitor the occurrence and characteristics of hereditary brain calcification. During the study, participants will undergo assessments including CT scans to measure calcification levels and regular follow-ups to track changes. Researchers will record the incidence of hereditary brain calcification and gather clinical and genetic data. The study also involves obtaining informed consent and ensuring participants adhere to scheduled visits and procedures throughout the observation period.
CONDITIONS
Brief Title
A Registered Cohort Study on Brain Calcification
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with brain calcium deposit(s) based on examinations of CT scans
- Patients with total calcification score(TCS) greater than the physiological threshold
- Relatives of brain calcification patients
- Unrelated healthy controls
- Participants or Parent(s)/legal guardian(s) willing and able to complete the informed consent process
You will not qualify if you...
- Brain calcification caused by specific secondary factors such as infection, poisoning, and trauma
- Participants declining or unable to comply with trial procedures and visit schedule
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 20 years
Participants are observed over time to monitor the incidence and progression of brain calcification.
Visits scheduled periodically throughout the study duration
Trial Site Locations
Total: 1 location
1
Department of Neurology, First Affiliated Hospital Fujian Medical University
Fuzhou, Fujian, China, 350005
Actively Recruiting
Research Team
Y
Yi Lin, PhD
W
Wan-Jin Chen, PhD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
Frequently Asked Questions
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