Actively Recruiting
Observational Study on Sleep Disorders in Adults with Neurodegenerative Diseases
Led by Fujian Medical University Union Hospital · Updated on 2025-01-22
500
Participants Needed
1
Research Sites
N/A
Total Duration
AI-Summary
What this Trial Is About
Cognitive problems often occur in people with neurodegenerative diseases. Researchers are exploring how sleep disorders relate to the progression of these diseases by studying their clinical signs, brain imaging, and biological markers. This observational study aims to better understand the mechanisms behind sleep problems in neurodegenerative conditions. Participants will have assessments including neuropsychological tests, brain MRI scans, and electroencephalograms. Biological samples will also be collected to measure markers like plasma Ab2-42 levels. These evaluations will help observe changes in sleep quality, cognitive function, heart rate variability, and other relevant outcomes over time. People in the study will undergo baseline and follow-up tests such as the Pittsburgh Sleep Quality Index PSQI, Montreal Cognitive Assessment MoCA, and Addenbrookes Cognitive Examination ACE-III. Researchers will monitor sleep patterns and biological markers to track disease progression. The study includes adults aged 30 to 80 years and will continue through June 2030, providing long-term data on sleep disorders linked to neurodegeneration.
CONDITIONS
Brief Title
A Registered Cohort Study on Neurodegenerative Associated With Sleep Disorder.
Research Team
X
Xiaodong Pan, Doctor
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