Actively Recruiting
Registering Genomics and Imaging of Tumors (ReGIT)
Led by Indiana University · Updated on 2025-09-15
20
Participants Needed
1
Research Sites
469 weeks
Total Duration
On this page
Sponsors
I
Indiana University
Lead Sponsor
C
Children's Hospital of Philadelphia
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study is investigating how brain tumors might mutate over time, and whether new brain imaging tools like MRI and PET can predict these mutations.
CONDITIONS
Official Title
Registering Genomics and Imaging of Tumors (ReGIT)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Be between 18 and 89 years old
- Have a radiological diagnosis or suspicion of WHO Grade II-IV glioma
- Have not received treatment except possibly a previous biopsy for the glioma
- Plan to undergo surgical removal and biopsy of the brain tumor
- Have enough tumor tissue so that at least two biopsy samples can be collected
- Be able to read and write in English
- Be able to lie on your back for up to 80 minutes
- Be able to hold still during MRI procedures
- Have signed the consent form or have a legally authorized representative who has signed
You will not qualify if you...
- Have conditions preventing MRI completion, such as claustrophobia, pacemaker, metal implants, or pregnancy
- Have serious unstable medical or mental illness
- Have insufficient tumor tissue for at least two biopsy samples
- Have medical reasons to avoid any study procedures
- Have not read, signed, or do not understand the consent form
- Are currently pregnant
- Are at high risk for nephrogenic systemic fibrosis and cannot follow the contrast agent dosing protocol
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Indiana University School of Medicine
Indianapolis, Indiana, United States, 46202
Actively Recruiting
Research Team
J
Jason Parker, PhD
CONTACT
J
Jason Parker, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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