Improving Heart Failure Treatment Using Registry Screening to Identify Needs for Medication, Device Therapies, and Physiotherapy

What this Trial Is About

Researchers are evaluating ways to improve treatment for patients with heart failure with reduced ejection fraction HFrEF, a condition where the heart does not pump blood effectively. The study aims to identify patients who need better medication management, screening and treatment for iron deficiency, consideration for heart devices like CRT or ICD, and referral to physiotherapy. This project uses the Swedish Heart Failure Registry to find patients who may benefit from these interventions and compares outcomes to a similar group not receiving this screening. The study involves screening 500 patients enrolled in the registry to check if they need starting or increasing heart failure medications, iron deficiency screening, device therapy, or physiotherapy referrals. These patients outcomes will be compared to 500 control patients not enrolled in the registry and not receiving this targeted screening. Treatments assessed include drug initiation or dose increases for several heart failure medications and referrals for device therapy and physiotherapy. Participants will be monitored for one year from the start of the intervention or from the index date for controls. Researchers will track how many patients experience treatment optimization events, including medication changes, device referrals, and iron deficiency screening. Data on referrals for physiotherapy will also be collected. The study ensures participants can give informed consent and monitors safety and adherence throughout the study period ending in June 2026.

Registry BAsed Optimization Of Therapy in Heart Failure