Actively Recruiting

Phase Not Applicable
Age: 8Years - 18Years
All Genders
NCT06396325

A Registry Based Randomized-Controlled Trial of an Upper Limb Exergaming Intervention for Children and Adolescents With Spinal Muscular Atrophy

Led by Maryam Oskoui, MD, MSc, FRCPC, FAAN · Updated on 2025-07-08

22

Participants Needed

5

Research Sites

165 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a multisite randomized controlled registry-based trial to evaluate the efficacy of an 8-week home-based exergaming intervention as compared to usual care on occupational satisfaction of children and youth (8-18 years old age) with spinal muscular atrophy (SMA).

CONDITIONS

Official Title

A Registry Based Randomized-Controlled Trial of an Upper Limb Exergaming Intervention for Children and Adolescents With Spinal Muscular Atrophy

Who Can Participate

Age: 8Years - 18Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Confirmed genetic diagnosis of 5q SMA
  • Age at screening: Aged 8-18 years old
  • Ability to sit independently without support for at least 10 seconds
  • Score of at least 2 points in entry item A of the RULM (can raise 1 or 2 hands to the mouth but cannot raise a 200 g weight to the mouth)
  • Receiving disease-modifying therapy
  • Signed informed consent form (ICF)
Not Eligible

You will not qualify if you...

  • Unable to comply with study procedures before randomization
  • Severe scoliosis or contractures interfering with gameplay or functional assessments
  • Planned orthopedic surgery 6 months before or during the 16-week study period
  • Inability to read in English or French

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 5 locations

1

Alberta Children's Hospital

Calgary, Alberta, Canada

Actively Recruiting

2

BC Children's Hospital

Vancouver, British Columbia, Canada

Actively Recruiting

3

IWK Health Services

Halifax, Nova Scotia, Canada

Actively Recruiting

4

Hospital for SickKids

Toronto, Ontario, Canada

Actively Recruiting

5

Centre de readaptation Marie-Enfant

Montreal, Quebec, Canada

Actively Recruiting

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Research Team

M

Mbaye Ndiaye

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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A Registry Based Randomized-Controlled Trial of an Upper Limb Exergaming Intervention for Children and Adolescents With Spinal Muscular Atrophy | DecenTrialz