Actively Recruiting
The T-cell Lymphoma Master Repository: A Prospective Databank of Patients With T-cell Lymphoma Including Clinical Data and Tumor Samples
Led by Memorial Sloan Kettering Cancer Center · Updated on 2026-05-20
1000
Participants Needed
26
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are collecting detailed information in a registry to better understand various types of mature T-cell and natural killer (NK)-cell lymphomas. This observational study aims to improve knowledge about these rare blood cancers by creating a comprehensive database that includes clinical information and tumor samples from participants. The study is sponsored by Memorial Sloan Kettering Cancer Center and focuses on multiple specific T-cell lymphoma subtypes as defined by recognized classification guidelines. Participants with confirmed mature T-cell or NK-cell lymphoma may choose to provide optional blood and nail samples for future research and biobanking. The study does not involve experimental treatments but gathers data prospectively from individuals meeting strict diagnostic criteria, including those receiving systemic therapy for certain cutaneous lymphoma types. This approach supports long-term data collection rather than testing new therapies. During the study, participants will have clinical data and tumor specimens collected and recorded. Researchers will track the number of participants contributing to the T-cell Lymphoma Master Repository over a 10-year period. The study involves ongoing follow-up to measure disease status and treatment response, with no direct intervention required. Participation helps build a resource to advance future research and understanding of these lymphomas.
CONDITIONS
Brief Title
A Registry for People With T-cell Lymphoma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Provided written informed consent
- Have an adequate fresh or archival tumor biopsy or plan to obtain one
- Diagnosed with a mature T-cell or natural killer (NK)-cell lymphoma matching recognized criteria, including types such as T-cell prolymphocytic leukemia, aggressive NK-cell leukemia, adult T-cell leukemia/lymphoma, mycosis fungoides (stage IB or higher and receiving active therapy), Sézary syndrome, and others listed
- For mycosis fungoides, primary cutaneous anaplastic large cell lymphoma, or primary cutaneous acral CD8+ T-cell lymphoma, must be receiving systemic therapy
You will not qualify if you...
- Diagnosed with mycosis fungoides, primary cutaneous anaplastic large cell lymphoma, or primary cutaneous acral CD8+ T-cell lymphoma but not receiving systemic therapy
- Unable to provide prospective data, measure response, or complete follow-up assessments as judged by the treating physician
- Patients already in clinical trials may still participate, and participation here does not exclude other trials or vice versa without physician judgment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 10 years
Participants with T-cell lymphoma are observed over time, including optional provision of blood and nail samples for biobanking and future research.
Visits as needed for data collection and sample provision
Trial Site Locations
Total: 26 locations
1
City of Hope Cancer Center (Data collection only)
Duarte, California, United States, 91010
Not Yet Recruiting
2
UNIVERSITY OF CALIFORNIA SAN DIEGO (Data collection only)
San Diego, California, United States, 92103
Not Yet Recruiting
3
University of California San Francisco (Data collection only)
San Francisco, California, United States, 94143
Not Yet Recruiting
4
Stanford University Medical Center (Data collection only)
Stanford, California, United States, 94305-5408
Not Yet Recruiting
5
University of Colorado (Data Collection Only)
Aurora, Colorado, United States, 80045
Not Yet Recruiting
6
Yale University (Data Collection Only)
New Haven, Connecticut, United States, 06511
Not Yet Recruiting
7
University of Miami (Data Collection Only)
Miami, Florida, United States, 33136
Not Yet Recruiting
8
Moffitt Cancer Center (Data Collection Only)
Tampa, Florida, United States, 33612
Not Yet Recruiting
9
Emory University (Data Collection Only)
Atlanta, Georgia, United States, 30322
Not Yet Recruiting
10
Northwestern Medicine (Data Collection)
Chicago, Illinois, United States, 60611
Not Yet Recruiting
11
Massachusetts General Hospital (Data Collection Only)
Boston, Massachusetts, United States, 02114
Not Yet Recruiting
12
Dana Farber Cancer Institute (Data Collection Only)
Boston, Massachusetts, United States, 02115
Not Yet Recruiting
13
Mayo Clinic (Data Collection Only)
Rochester, Minnesota, United States, 55905
Not Yet Recruiting
14
Washington University (Data Collection Only)
St Louis, Missouri, United States, 63110
Not Yet Recruiting
15
University of Nebraska (Data collection only)
Omaha, Nebraska, United States, 68198-7680
Not Yet Recruiting
16
Memorial Sloan Kettering at Basking Ridge (All protocol activities)
Basking Ridge, New Jersey, United States, 07920
Actively Recruiting
17
Memorial Sloan Kettering Monmouth (All protocol activities)
Middletown, New Jersey, United States, 07748
Actively Recruiting
18
Memorial Sloan Kettering Cancer Center @ Suffolk-Commack (All protocol activities)
Commack, New York, United States, 11725
Actively Recruiting
19
Memorial Sloan Kettering Westchester (All protocol activities)
Harrison, New York, United States, 10604
Actively Recruiting
20
Weill Cornell Medical Center (Data Collection Only)
New York, New York, United States, 10021
Not Yet Recruiting
21
Memorial Sloan Kettering Cancer Center (All Protocol Activities)
New York, New York, United States, 10065
Actively Recruiting
22
Memorial Sloan Kettering Nassau (All protocol activities)
Uniondale, New York, United States, 11553
Actively Recruiting
23
Ohio State University (Data Collection Only)
Columbus, Ohio, United States, 43210
Not Yet Recruiting
24
University of Pennsylvania (Data Collection Only)
Philadelphia, Pennsylvania, United States, 19104
Not Yet Recruiting
25
Thomas Jefferson University Hospital (Data collection only)
Philadelphia, Pennsylvania, United States, 19107
Not Yet Recruiting
26
MD Anderson Cancer Center (Data Collection Only)
Houston, Texas, United States, 77030
Not Yet Recruiting
Research Team
S
Steven Horwitz, MD
A
Alison Moskowitz, MD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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