Actively Recruiting

Age: 18Years +
All Genders
NCT05665556

REgistry of Pulmonary Arterial Hypertension Associated With CONNECTIVE Tissue Diseases (RECONNECTIVE)

Led by Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran · Updated on 2023-06-29

170

Participants Needed

1

Research Sites

258 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The RECONNECTIVE Registry is an observational single center study, focused on the subgroup of precapillary pulmonary hypertension related to connective tissue diseases. All patients will have hemodynamic confirmation by right heart catheterization and will be follow-up for at least 5 years from admission. All patients diagnosed with Group I Pulmonary Arterial Hypertension (PAH) associated with Connective Tissue Diseases (CTD) and Group IV Pulmonary Hypertension (PH) with CTD will be included. The purpose of the registry is to learn and understand the clinical outcomes and natural history of the pulmonary arterial hypertension in this subgroup of patients to improve the medical care and treatment.

CONDITIONS

Official Title

REgistry of Pulmonary Arterial Hypertension Associated With CONNECTIVE Tissue Diseases (RECONNECTIVE)

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients diagnosed with Group I pulmonary arterial hypertension associated with connective tissue diseases
  • Patients diagnosed with Group IV pulmonary arterial hypertension with connective tissue diseases and chronic thromboembolic pulmonary disease confirmed by ventilation/perfusion scan or CT pulmonary angiogram
  • Patients who have received at least three months of anticoagulation therapy if diagnosed with chronic thromboembolic pulmonary disease
  • Patients diagnosed with connective tissue disease based on American College of Rheumatology criteria
  • Precapillary pulmonary hypertension confirmed by right heart catheterization with mean pulmonary arterial pressure over 20 mm Hg, pulmonary arterial wedge pressure 15 mm Hg or less, and pulmonary vascular resistance 2.0 Wood units or higher
Not Eligible

You will not qualify if you...

  • Patients who meet criteria for pulmonary hypertension Groups II, III, or V

AI-Screening

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Trial Site Locations

Total: 1 location

1

Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán

Mexico City, Mexico, 14080

Actively Recruiting

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Research Team

J

Jose Luis Hernandez Oropeza, PhD

CONTACT

J

Jose de Jesus Rodriguez Andoney, M.Sc.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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