Registry Study to Identify Biomarkers for Diagnosing and Monitoring Takayasus Arteritis in Adults

What this Trial Is About

Takayasu arteritis is a rare, chronic inflammation of the large arteries such as the aorta and its main branches. This condition can cause narrowing, blockage, or stretching of these vessels, sometimes leading to aneurysms. It often affects young Asian women and may remain undetected until vascular problems arise. Because many people with Takayasu arteritis show no clear symptoms despite active disease, researchers are seeking new biomarkers to improve diagnosis and monitor disease activity, aiming to better understand its underlying biological processes. This observational study focuses on identifying these biomarkers by enrolling individuals diagnosed with or suspected of having Takayasu arteritis. Participants include cases who meet specific classification criteria and controls. The study collects data retrospectively and prospectively, using imaging techniques like vascular magnetic resonance angiography or computed tomography angiography instead of traditional angiography. The study monitors disease status over time to uncover biochemical markers linked to disease activity. Participants will have their diagnosis and disease activity recorded from medical records within about three to six months after sample collection. These records and follow-up visits help assess the progression and activity of the disease. The study involves reviewing clinical data and imaging results to support biomarker discovery. Participation duration and follow-up depend on individual cases, with researchers closely tracking disease status to enhance understanding of Takayasu arteritis.

A Registry Study on Biomarkers of Takayasu's Arteritis (ARSBTA)