Actively Recruiting

Age: 50Years - 79Years
All Genders
ID04137549

Registry Study on Control Nocturnal Hypertension to Reach the Target (CONTROL-NHT)

Led by Shanghai Institute of Hypertension · Updated on 2025-01-06

4500

Participants Needed

1

Research Sites

369 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Ambulatory blood pressure monitoring (ABPM) has become an important tool for diagnosing hypertension by measuring blood pressure throughout daily activities and sleep. This research focuses on the significance of nocturnal blood pressure, which has been found to better predict fatal and non-fatal cardiovascular events like stroke and heart attack, especially in patients on medication. The study aims to understand how controlling nighttime blood pressure affects cardiovascular outcomes in patients with nocturnal hypertension. The study collects nationwide prospective data on patients diagnosed with nocturnal hypertension who are using antihypertensive drugs. Participants have undergone 24-hour ABPM with validated equipment to confirm elevated nighttime blood pressure. The research involves monitoring participants over time to compare cardiovascular event rates based on how well their nocturnal blood pressure is controlled. Participants will be followed for up to three years, during which researchers will record the time to any fatal or non-fatal cardiovascular event. The study requires participants to provide medical history and biochemical test results within six months and to consent to the study. This long-term observation will help assess the impact of nighttime blood pressure management on heart health and stroke risk.

CONDITIONS

Official Title

Registry Study on "Control Nocturnal Hypertension to Reach the Target "

Who Can Participate

Age: 50Years - 79Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 50-79 years old
  • Clinical diagnosis of hypertension with use of antihypertensive drugs
  • Nocturnal hypertension defined as nocturnal systolic blood pressure 64 130 mmHg and/or nocturnal diastolic blood pressure 64 80 mmHg
  • 24-hour ambulatory blood pressure monitoring performed with validated equipment
  • Willing to provide disease history and blood biochemical test data from within 6 months
  • Signed informed consent
Not Eligible

You will not qualify if you...

  • Not using antihypertensive drugs
  • Hospitalized hypertension patients
  • Patients who are non-compliant

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Ruijin Hospital

Shanghai, Shanghai Municipality, China, 200025

Actively Recruiting

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Research Team

Y

Yan Li, MD,PhD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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