Actively Recruiting
A Registry Study of Intracranial Atherosclerotic Stenosis Treatment by Intracranial Drug-eluting Stenting in China
Led by Sino Medical Sciences Technology Inc. · Updated on 2025-04-01
1000
Participants Needed
5
Research Sites
319 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The primary objective of this trial is to evaluate the long-term safety and efficacy of the NOVA intracranial drug-eluting stent system in "real world" patients with intracranial atherosclerotic stenosis.
CONDITIONS
Official Title
A Registry Study of Intracranial Atherosclerotic Stenosis Treatment by Intracranial Drug-eluting Stenting in China
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Males or females between 18 and 80 years of age
- Symptomatic intracranial arteriosclerosis stenosis with reference diameter 2.25-4.00mm
- Intracranial artery stenosis (≥70%) confirmed by digital subtraction angiography (DSA)
- Voluntary participation with signed informed consent form
You will not qualify if you...
- Surgery within previous 30 days or planned major surgery in next 90 days
- Acute hemorrhagic stroke within 3 months
- Baseline modified Rankin Scale (mRS) score for disabling stroke greater than 3
- Target vessel severely calcified and closely related to stenosis
- Non-atherosclerotic diseases such as arterial dissection, Moya Moya disease, vascular inflammatory lesions, autoimmune diseases, post-irradiation, postpartum status, developmental or genetic abnormalities
- Suspected ischemic event due to embolism from extracranial segment or cardiogenic embolism
- Target artery's supplying artery stenosis greater than 50%
- Presence of intracranial tumors or arteriovenous malformations
- Allergies to heparin, aspirin, clopidogrel, contrast agents, anesthetics, or stent components
- Pregnant or lactating women
- Unable to complete follow-up due to mental illness, cognitive or emotional disorders
- Investigator's judgement that participation is not suitable
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 5 locations
1
First People's Hospital of Chenzhou
Chenzhou, China
Actively Recruiting
2
Ganzhou People's Hospital
Ganzhou, China
Actively Recruiting
3
Jinhua Municipal Central Hospital
Jinhua, China
Actively Recruiting
4
The First Affiliated Hospital of Ningbo University
Ningbo, China
Actively Recruiting
5
Shanxi Cardiovascular Hospital
Shanxi, China
Actively Recruiting
Research Team
Z
Zhongrong Miao, MD
CONTACT
B
Baixue Jia, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here